Results 241 to 250 of about 980,417 (331)
Trametinib in Adults with Neurofibromatosis Type 1‐Related Symptomatic Plexiform Neurofibromas
Objective Mitogen‐activated protein kinase kinase inhibitors have shown promising results in treatment of plexiform neurofibromas in neurofibromatosis type 1 patients, but data in adults are limited. The aim of this phase 2 study was to investigate the efficacy and safety of trametinib in adults with neurofibromatosis type 1.
D. Christine Noordhoek +7 more
wiley +1 more source
Pathways of influence on health-promoting lifestyles in older adults with coronary heart disease: a cross-sectional study. [PDF]
Tian Z +5 more
europepmc +1 more source
Healthier lifestyles after retirement in Europe? Evidence from SHARE
M. Celidoni, Vincenzo Rebba
semanticscholar +1 more source
Objective Antiseizure medication (ASM) use during pregnancy has increased over the past decade. However, evidence linking prenatal ASM exposure to neurodevelopmental disorders (NDDs) in offspring remains inconsistent. This study evaluated whether prenatal ASM exposure increases the risk of NDDs in children.
Odile Sheehy +13 more
wiley +1 more source
Lifestyles shape genome size and gene content in fungal pathogens. [PDF]
Fijarczyk A +3 more
europepmc +1 more source
Objective The evidence regarding adherence to dietary patterns and Parkinson's disease (PD) risk is inconsistent. Because of the long prodromal PD phase, reverse causation represents a major threat to investigations of diet in relation to PD. We examined whether adherence to the Mediterranean (MED) and Mediterranean‐Dietary Approaches to Stop ...
Mariem Hajji‐Louati +6 more
wiley +1 more source
Mobile lifestyles: Conceptualizing heterogeneity in mobile youth culture
M. V. Abeele
semanticscholar +1 more source
Objective Sporadic late‐onset Alzheimer's disease (AD) is characterized by a long pre‐clinical phase where amyloid‐beta (Aβ) and tau begin to accumulate in the brain. The primary objective was to determine the age at which AD starts by finding the average population age when both positron emission tomography (PET) Aβ (Aβ‐PET) and plasma Aβ42/40 become ...
Rodrigo Cánovas +29 more
wiley +1 more source
Healthy lifestyles, screening, and breast cancer mortality in women with different risk of disease. [PDF]
Yang H +7 more
europepmc +1 more source
Sex‐Specific Genetic Architecture of ALS: Evidence of a Female Protective Effect?
Background Amyotrophic lateral sclerosis (ALS) shows sex differences in incidence and age of onset, yet the underlying biological mechanisms remain poorly understood. Methods We investigated sex‐specific genetic architecture in an Italian ALS cohort with whole‐genome sequencing (1,333 ALS cases, 755 controls).
Maurizio Grassano +20 more
wiley +1 more source

