Results 21 to 30 of about 133,004 (235)

Creating a healthy and sustainable food environment to promote plant-based food consumption: clear barriers and a gradual transition

BMC Public Health
Background A shift away from diets high in animal-based foods towards diets high in plant-based foods is desirable considering human health, environmental sustainability, and animal welfare.
Ward S. van Hoeven, Monique Simons, Melina T. Czymoniewicz-Klippel, Harm Veling   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Neurocomputational mechanisms of food and physical activity decision-making in male adolescents

Scientific Reports, 2023
We examined the neurocomputational mechanisms in which male adolescents make food and physical activity decisions and how those processes are influenced by body weight and physical activity levels.
Seung-Lark Lim, Amanda S. Bruce, Robin P. Shook   +2 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

The role of the workplace food environment in eating behaviours of employees at small and medium-sized enterprises: a qualitative study in the Netherlands

BMC Public Health
Background Workplace food environments play a pivotal role in encouraging healthy and sustainable food choices. However, research on food environments in small and medium-sized enterprises (SMEs) without a workplace cafeteria is scarce, with much of the ...
Lisanne Geboers, Sanne K. Djojosoeparto, Frédérique C. Rongen, Maartje P. Poelman   +3 more
doaj   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

O the places rural children will go…to get physical activity: a cross sectional analysis

BMC Public Health
Purpose Youth living in rural areas have higher risk for overweight/obesity. It is important to understand where these children engage in moderate-to-vigorous physical activity (MVPA) and sedentary time to encourage or intervene on activity in specific ...
Bethany Forseth, Jordan A. Carlson, Adrian Ortega, Chelsea Steel, Brittany Lancaster, Lauren K. Fitzpatrick, Qianxia Jiang, Ann M. Davis   +7 more
doaj   +1 more source

Stakeholder dialogue on dilemmas at work as a workplace health promotion intervention including employees with a low SEP: a Responsive Evaluation

BMC Public Health, 2022
Background The aim of this study was to evaluate the perceived changes of an innovative workplace health promotion intervention and evaluation. In this study, a bottom-up approach was taken to define the central themes and relevant outcomes of an ...
Hanneke van Heijster, Jantien van Berkel, Cécile R. L. Boot, Tineke Abma, Emely de Vet   +4 more
doaj   +1 more source

LIFESTYLES

As competition for water increases in California in the coming years, potential resolution of the water imbalance will be focused not only on technical "fixes" but also on changes in lifestyles which affect the patterns of consumption and development of water. Different patterns of water use are evident in California's culture and tradition.
Bradshaw, TK, Vine, E, Barth, G
openaire   +2 more sources