Results 71 to 80 of about 980,417 (331)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Determinants, behaviour change techniques and pedagogical approaches used in secondary school-based food and nutrition programmes: a qualitative study of the SWITCH project

BMC Public Health
Background Food and nutrition programmes at secondary schools have the potential to improve public and planetary health, as they target a wide range of adolescents.
Anouk Mesch, Madelief Engels, Sanne Raghoebar, Laura H. H. Winkens, Judith Gulikers, Renate Wesselink, Annemien Haveman-Nies   +6 more
doaj   +1 more source

Health Lifestyles in Late Middle Age

Research on Aging, 2019
A growing body of work identifies distinct health lifestyles among children, adolescents, and young adults and documents important social correlates. This study contributes to that line of research by identifying the health lifestyles of U.S.
W. Cockerham, Joseph D Wolfe, Shawn Bauldry   +2 more
semanticscholar   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

The food environment through the eyes of adolescents: exploring socioecological factors and opportunities for healthy and sustainable food choices

BMC Public Health
Background Although it is evident that current food environments do not facilitate healthy and sustainable diets, it is still largely unknown how adolescents navigate their food environments during the school week. This study explored how adolescents, in
Anouk Mesch, Femke Hoefnagels, Judith Gulikers, Renate Wesselink, Laura H.H. Winkens, Sanne Raghoebar, Annemien Haveman-Nies   +6 more
doaj   +1 more source

Switching Lifestyles Is an in vivo Adaptive Strategy of Bacterial Pathogens

Frontiers in Cellular and Infection Microbiology, 2019
Gram-positive and Gram-negative pathogens exist as planktonic cells only at limited times during their life cycle. In response to environmental signals such as temperature, pH, osmolality, and nutrient availability, pathogenic bacteria can adopt varied ...
Stuti K. Desai, L. Kenney
semanticscholar   +1 more source

Higher Amyloid and Tau Burden Is Associated With Faster Decline on a Digital Cognitive Test

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective A 2‐min digital clock‐drawing test (DCTclock) captures more granular features of the clock‐drawing process than the pencil‐and‐paper clock‐drawing test, revealing more subtle deficits at the preclinical stage of Alzheimer's disease (AD). A previous cross‐sectional study demonstrated that worse DCTclock performance was associated with
Jessie Fanglu Fu, Talia Robinson, Marina Rodriguez Alonso, Adela Francis Malave, Roos J. Jutten, Michael J. Properzi, Brian C. Healy, Jackson C. Thompson, Grace Del Carmen Montenegro, Emma Thibault, Dana Penney, Randall Davis, Reisa A. Sperling, Kathryn V. Papp, Keith A. Johnson, Julie C. Price, Dorene M. Rentz   +16 more
wiley   +1 more source

Voicing residents’ perception of (commercial) food cues in outdoor public spaces: a photovoice study

BMC Public Health
Background (Commercial) food cues in outdoor public spaces are environmental drivers of unhealthy diets. This study aimed to explore residents’ perceptions of food cues in outdoor public spaces in relation to their perceived food environment, eating ...
Tamika M. Wopereis, Kirsten J. Roman, Sanne K. Djojosoeparto, Maartje P. Poelman   +3 more
doaj   +1 more source

Food availability, perceived food environment and social norm perceptions of healthy and vegetarian food consumption at a public music festival in the Netherlands: a cross-sectional study

BMJ Nutrition, Prevention & Health
Objective To gain insight into the food availability, the perceived food environment, and social norm perceptions in favour of healthy and vegetarian food consumption at a festival.Design Two cross-sectional substudies were conducted to audit food and ...
Emely de Vet, Tamika M Wopereis, Frédérique C Rongen, Maartje P Poelman   +3 more
doaj   +1 more source

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source