Results 31 to 40 of about 186,534 (247)

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and 1‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

Arthritis Care &Research, EarlyView.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension phase).
Fabrizio De Benedetti, Inmaculada C. Penadés, Irina Nikishina, Ivan Foeldvari, Alberto J. Spindler, Anna Kozlova, Nadina Rubio‐Pérez, Pierre Quartier, Zbigniew Żuber, Raul Barria, Daniel Clemente, Gabriel V. Cornejo, Katherine Marzan, Nancy Liu, Christine Xu, Stephen DiMartino, Angeliki Giannelou, Fei Cao‐Ghoul, Bolanle Akinlade, Lydie Baret‐Cormel   +19 more
wiley   +1 more source

Does Long‐Term Lower Extremity Strength Training in Adults With Knee Osteoarthritis and Varus Alignment Reduce Knee Joint Loading During Gait?

Arthritis Care &Research, EarlyView.
Objective We examined whether 18 months of strength training in individuals with knee varus alignment and medial tibiofemoral osteoarthritis (OA) reduced knee joint loads during walking compared to an attention control group. Methods This study was a secondary analysis of a randomized clinical trial that compared the effects of strength training to a ...
Stephen P. Messier, Matthew N. Vigliotti, Paige E. Rice, Brian Pietrosimone, Shannon L. Mihalko, Edward H. Ip, Richard F. Loeser, David J. Hunter, Ali Guermazi, Ryan Hill, Santiago Saldana, Kim L. Bennell, Paul DeVita   +12 more
wiley   +1 more source

Current treatment approaches for ankle ligament injuries: what has changed?

Medicine Science, 2017
Because of inadequate and unsuccesful management of ALI, undesired chronic disabilities may unluckily be observed. Treatment of these patients should be planned comprehensive and detailed depending on patient’s diagnosis, injury’s severity and stage ...
Bulent Karslioglu, Taner Dandinoglu, Yusuf Erdem, Ozgur Dandin   +3 more
doaj   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

Interconnected Porous Hydrogels with Tunable Anisotropy Through Aqueous Emulsion Bioprinting

Advanced Functional Materials, EarlyView.
A 3D bioprintable microporous bioink is developed using an aqueous two‐phase system (ATPS) composed of extracellular matrix (ECM) mimetic biopolymers. The ATPS bioink enables the fabrication of interconnected porous architectures with up to 70% porosity, supporting long‐term cell viability and 3D cell alignment, enabling a simultaneous generation of ...
Hugo Edgar‐Vilar, Francisca P. Correia, Inês M. Freitas, Vítor M. Gaspar, João F. Mano   +4 more
wiley   +1 more source

Precontoured Locking Compression Plate with Titanium Alloy Cable System: In Treatment of Neer Type IIb Distal Clavicle Fracture

Orthopaedic Surgery, 2021
Objective To describe a new method which involves anatomical distal clavicle plate fixation and titanium alloy cable system‐augmented coracoclavicular ligament reconstruction to manage Neer type IIb distal clavicle fracture.
Zheng Xie, Mengxiong Song, Jun Zhou, Gang Yin, Haodong Lin   +4 more
doaj   +1 more source

Safety and Performance of Titanium Suture Anchors Used in Knee Ligament Repair Procedures

Medicina, 2021
Injuries to the knee ligaments can be particularly disabling in young patients, given the risk of long-term disability if adequate fixation is not achieved during initial repair. The TWINFIX™ titanium (Ti) suture anchor with ULTRABRAID™ Suture (Smith and
Antonio Maestro, Iván Pipa, Nicolás Rodríguez, Carmen Toyos, Marcelino Torrontegui-Duarte, Cesar Castaño   +5 more
doaj   +1 more source

Scapholunate Ligament Reconstruction [PDF]

Journal of Wrist Surgery, 2013
Background Scapholunate reconstruction poses a challenge to orthopedic surgeons. Materials and Methods Prospective cohort. Description of Technique Our technique for scapholunate (SL) reconstruction involves ligament reconstruction utilizing a portion of the flexor carpi radialis tendon rerouted via transosseous tunnels across the scaphoid, lunate, and
Ross, Mark, Loveridge, Jeremy, Cutbush, Kenneth, Couzens, Greg   +3 more
openaire   +3 more sources

Structural Porosity and Low Mineral Density in Enamel Rods Drive Molar Incisor Hypomineralisation

Advanced Functional Materials, EarlyView.
This study uses advanced imaging modalities on multiple length scales to show that molar‐incisor hypomineralization does not present as a locally homogeneous pathology. Instead, microstructural defects, characterized through non‐mineralized, protein‐rich sheaths and an altered mineral structure in between prism rods, resulting in local differences in ...
Katharina Jähn‐Rickert, Johannes Krug, Gudrun Lotze, Imke A.K. Fiedler, Diana Freund, Ezgi Deniz Türkoğlu, Christine Plumeyer, Felix N. von Brackel, Anton Davydok, Manfred Burghammer, Thomas Beikler, Thomas F. Keller, Katrin Bekes, Elizabeth A. Zimmermann, Björn Busse   +14 more
wiley   +1 more source

Application of decellularized tissue for soft-hard interregional regeneration

Frontiers in Bioengineering and Biotechnology
Decellularized tissue refers to extracellular matrix (ECM) derived from living tissue by removing the cellular components and is used for tissue regeneration.
Mika Suzuki, Tsuyoshi Kimura, Tsuyoshi Kimura, Yoshihide Hashimoto, Yoshihide Hashimoto, Akio Kishida   +5 more
doaj   +1 more source