Results 41 to 50 of about 47,360 (313)

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

Diagnostic imaging of the canine stifle [PDF]

, 2012
C
Gielen, Ingrid, van Bree, Henri, Van Ryssen, Bernadette   +2 more
core   +1 more source

Knee pain [PDF]

, 2006
JC is a 13 year old boy who presented with a 3 week history of anterior right knee pain. Pain is activity related and brought on whenever JC plays football or basketball. He never needed to stop from any particular activity because of the pain.
Formosa, Aaron
core   +1 more source

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

Advanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu, Wen Geng, Zhi Du, Yifan Du, Di Wu, Bide Tong, Huaizhen Liang, Xingyu Zhou, Zixuan Ou, Junyu Wei, Kun Wang, Yu Song, Wenbin Hua, Yan Xu, Wencan Ke, Bingjin Wang, Cao Yang   +16 more
wiley   +1 more source

Deciphering and Targeting the Schwannoma‐Neuron‐Macrophage Crosstalk for the Treatment of Schwannomatosis and Associated Pain

Advanced Science, EarlyView.
We established patient‐derived SWN cell lines and orthotopic PDX models that recapitulate patient pain phenotypes, alongside a novel intravital DRG imaging platform to track macrophage infiltration and neuronal pain responses. Using these models, we define HMGB1–CCL2–IL‐6 signaling crosstalk driving pain and identify EGF signaling as a key regulator of
Zhenzhen Yin, Limeng Wu, Yanling Zhang, Yao Sun, Grace Y. Lee, Simeng Lu, Xing Gao, John W. Chen, Sonu Subudhi, William Ho, Chao Zhu, Jun Ren, Gino B. Ferraro, Alona Muzikansky, Anat Stemmer‐Rachamimov, Jianren Mao, Scott R. Plotkin, Lei Xu   +17 more
wiley   +1 more source

Collagens - structure, function and biosynthesis. [PDF]

, 2003
The extracellular matrix represents a complex alloy of variable members of diverse protein families defining structural integrity and various physiological functions.
Aigner, T, Gelse, K, Poschl, E
core   +1 more source

Ultrastructural study of the extra-articular Leeds-Keio ligament prosthesis [PDF]

Journal of Clinical Pathology, 2005
Background: There have been several histological studies of the Leeds-Keio ligament in anterior cruciate ligament reconstruction, but there have been few of the Leeds-Keio ligament in the extra-articular portion. Aims/Methods: To report the histological and ultrastructural findings of two cases of ...
E, Nomura, M, Inoue, H, Sugiura
openaire   +2 more sources

Single‐Cell Atlas of Subchondral Bone Marrow Lesions Reveals Proteostasis Dysfunction as a Druggable Mechanism for Early Osteoarthritis

Advanced Science, EarlyView.
This study reveals that abnormal mechanical stress downregulates the expression of HSP70 and impairs proteasome function in osteoarthritic bone cells, leading to misfolded collagen I accumulation and ER stress. When intracellular proteostasis capacity is exceeded, USP19 mediates the secretion of misfolded proteins into the extracellular space ...
Hailun Xu, Ting He, Yu Qian, Jia Li, Bowei Ni, Xiaojie Xu, Huanbo Wang, Peng Wang, Guoqing Cao, Siqi Ying, Guangyu Ding, Rong Wang, Zenghui Gu, Wei Li, Zhentao Man, Houfeng Zheng, Zhaohua Zhu, Zhen Li, Qingjun Meng, Chao Zheng, Liu Yang   +20 more
wiley   +1 more source

Tendon stem/progenitor cells are promising reparative cell sources for multiple musculoskeletal injuries of concomitant articular cartilage lesions associated with ligament injuries

Journal of Orthopaedic Surgery and Research, 2023
Background Trauma-related articular cartilage lesions usually occur in conjunction with ligament injuries. Torn ligaments are frequently reconstructed with tendon autograft and has been proven to achieve satisfactory clinical outcomes.
Heyong Yin, Kelei Mao, Yufu Huang, Ai Guo, Lin Shi   +4 more
doaj   +1 more source

Histological evidence for a supraspinous ligament in sauropod dinosaurs [PDF]

, 2015
Supraspinous ossified rods have been reported in the sacra of some derived sauropod dinosaurs. Although different hypotheses have been proposed to explain the origin ofthis structure, histological evidence has never been provided to support or reject any
Abdalla O, Abdel Meguid EM, Barreto C, Bonaparte JF, Bonaparte JF, Campos D, Casal GA, Casal GA, Cerda IA, Cerda IA, Chinsamy A, Chinsamy-Turan A, Francillon-Vieillot H, García RA, Giménez O, Gomani M, Güner A, Hamdam TA, Hatcher JB, Henderson D, Heylings DJA, Horner JR, Janensch W, Janensch W, Kellner AWA, Mcintosh JS, Morocutti M, Novas FE, Osborn HF, Powell JE, Powell JE, Powell JE, Reid REH, Sandqvist AV, Strocchi R, Yayama T, You H-L, Zhang Y   +37 more
core   +2 more sources