Results 151 to 160 of about 321,470 (363)

Long noncoding RNA GCH1 mediates mitophagy via the PTEN‐induced kinase 1/Parkin pathway to drive chondrocyte dysfunction and cartilage degeneration in osteoarthritis

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The graphical abstract illustrates the role of lncRNA‐GCH1 in regulating mitophagy and its downstream effects on chondrocyte dysfunction and cartilage degradation in osteoarthritis (OA). Elevated lncRNA‐GCH1 stabilizes PINK1 protein, enhancing mitophagy and mitochondrial turnover.
Gang Zeng   +8 more
wiley   +1 more source

Novel Extraluminal silicone tracheal stent: Development and evaluation in a rabbit model of tracheomalacia

open access: yesAnimal Models and Experimental Medicine, EarlyView.
A novel extraluminal silicone stent was developed and applied in a rabbit model of tracheomalacia. The stent effectively maintained airway patency and minimized tissue reaction without causing cartilage damage. This approach may offer a safe and effective alternative for treating tracheal collapse in small animals.
Yoon‐Hee Ryu   +6 more
wiley   +1 more source

Trapeziometacarpal Joint Stability: The Evolving Importance of the Dorsal Ligaments

open access: yesClinical Orthopaedics and Related Research, 2014
James D. Lin, J. Karl, R. Strauch
semanticscholar   +1 more source

Advanced Contactless Bioassembly Approaches: Leveraging Sound, Optical, and Magnetic Fields

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review explores innovative contactless bioassembly techniques driven by sound, light, and magnetic fields, which enable the precise organization of cells, biomaterials, and bioactive substances into complex 3D structures. These technologies, crucial for in vitro modeling and regenerative medicine, are examined in detail, highlighting their ...
Micaela Natta   +4 more
wiley   +1 more source

Potential Application of a Water‐Soluble Fullerene C60 Decorated with Diethylene Glycol in Treatment of Osteoarthritis

open access: yesAdvanced NanoBiomed Research, EarlyView.
A new ethoxyethanol derivative of iminofullerene, F2, is synthesized and labeled with 99mTc to produce 99mTc‐F2. In vitro, compound F2 inhibits the activation of primary mouse bone marrow‐derived macrophages stimulated with lipopolysaccharide. Moreover, 99mTc‐F2 is selectively enriched in the injured joints of mice. Inflammatory macrophages play a role
Rui He   +6 more
wiley   +1 more source

Resolving Localized Plasmonic and Photonic Modes of Gold Nanosponges via Cathodoluminescence Spectroscopy

open access: yesAdvanced Physics Research, EarlyView.
Cathodoluminescence spectroscopy of gold nanosponges, together with polarimetry experiments, demonstrates the presence of a network of randomly positioned dipolar plasmonic resonances with a spatial extent of only a few nanometres. Abstract Localizing optical fields at deep sub‐wavelength scales has applications in ultra‐strong light‐matter ...
Paul H. Bittorf   +4 more
wiley   +1 more source

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