Results 271 to 280 of about 901,811 (316)

Fas ligand: receptor or ligand?

Apoptosis, 1999
In this review, we chronicle the discovery, biochemical characterization, and assignment of Fas (CD95) as receptor and Fas Ligand (FasL, CD95L) as ligand. We review the functional descriptions of the molecules as death-inducing receptor and ligand or as mediators of cell division and/or growth arrest.
M K, Newell, J, Desbarats
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The inductive effect and ligand–ligand interactions in mutual influence of ligands

Inorganica Chimica Acta, 1978
Abstract The inductive effect in series AF(n + 1)−5 and AF5Cln− (A = Si, P, S, Se) has been calculated by an approximate non-empiric method. The effect is directed primarily along the cis-coordinate; with isoelectronic compounds of one period elements it is growing along the period from the left to the right. The role of ligand–ligand interactions in
M.M. Gofman, V.I. Nefedov
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Nuclear-Receptor Ligands and Ligand-Binding Domains

Annual Review of Biochemistry, 1999
▪ Abstract  The determination of several structures of nuclear receptor ligand binding domains (LBD) has led to new insights into the mechanism of action of this very important class of receptors. This review describes and compares the different LBD structures and their relationship to the function of the nuclear receptors.
R V, Weatherman, R J, Fletterick, T S, Scanlan   +2 more
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Cannabinoid Receptors and Their Ligands: Ligand—Ligand and Ligand—Receptor Modeling Approaches

2005
The cannabinoid CB1 and CB2 receptors belong to the class A, rhodopsin-like family of GPCRs. Antagonists for each receptor sub-type, as well as four structural classes of agonists that bind to both receptors, have been identified. An extensive amount of structure-activity relationship information (SAR) has been developed for agonists and antagonists ...
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Supramolecular ligand–ligand and ligand–substrate interactions for highly selective transition metal catalysis

Dalton Transactions, 2011
The use of non covalent supramolecular ligand-ligand and ligand-substrate interactions in transition metal-catalysed transformations is a new, rapidly emerging area of research. Non-covalent interactions between monodentate ligands such as hydrogen bonding, coordinative bonding, ion pairing, π-π interactions and the formation of inclusion compounds ...
S. Carboni, C. Gennari, L. Pignataro, U. Piarulli   +3 more
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Interaction of Calreticulin with CD40 Ligand, TRAIL and Fas Ligand

Scandinavian Journal of Immunology, 2007
AbstractThe molecular chaperone calreticulin has been shown to bind C1q and mannan‐binding lectin (MBL), which are constituents of the innate immune defence system. C1q and MBL do not share a large sequence identity but have a similar overall molecular architecture: an N‐terminal triple‐helical collagen‐like domain and a C‐terminal globular domain with
Duus, K., Pagh, R.T., Holmskov, Uffe Laurits, Højrup, P., Skov, S., Houen, G.   +5 more
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Complexes of Polypyrazolylborate ligands

Journal of Organometallic Chemistry, 1972
Abstract Studies of the structures of [HB(pz)3](C5H5)(CO)2Mo and [Et2B(pz)2]-(C5H5)(CO)2Mo, where HB(pz)3 and Et2B(pz)2 represent the hydridotris(pyrazolyl)-borate and the diethylbis(pyrazolyl)borate groups respectively, have been carried out on solutions using infrared and PMR spectra.
J.L. Calderon, Alan Shaver, F.A. Cotton
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Ligand-Gated Channels

IEEE Transactions on Nanobioscience, 2005
Ligand-gated ion channels (LGICs) are fast-responding channels in which the receptor, which binds the activating molecule (the ligand), and the ion channel are part of the same nanomolecular protein complex. This paper will describe the properties and functions of the nicotinic acetylcholine LGIC superfamily, which plays a critical role in the fast ...
Barry, P. H., Lynch, J. W.
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Opioid Receptors and their Ligands

Current Topics in Medicinal Chemistry, 2004
This review gives a historical perspective, summarizing approximately 25 years of research on opioids. The "typical" opioid peptides produced in the brain, "atypical" opioids encrypted in milk protein or hemoglobin sequences, and extremely potent and selective opioids of amphibian origin are described.
Anna, Janecka, Jakub, Fichna, Tomasz, Janecki   +2 more
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The Selectins and Their Ligands

1993
Among the four major groups of cell adhesion molecules (CAMs) the selectins represent the smallest and most recently identified gene family (Lasky 1992; Vestweber 1992). In contrast to the three large families of the integrins, the immunoglobulin super gene family and the cadherins, the selectins consist of only three members: L-, E-, and P-selectin ...
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