Results 91 to 100 of about 427,156 (310)
Orbital Varix and Its Surgical Correction - A Case Report
Indian Journal of Plastic Surgery, 1993 A Young patient presented with left unilateral proptosis and Orbital venography was suggestive of orbital vari on left side. An easy and effective operative procedure was planned. The superficial veins around orbit were ligated. Result was acceptable and
Dr. P.K. Sharma +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Chemical Ligation for Molecular Imaging
Molecular imaging in living systems has become an important tool for understanding molecular processes and cellular events in preclinical settings.
Karatas, Hacer +3 more
core +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
TO THE QUESTION OF LIVER RESECTION
Креативная хирургия и онкология, 2017 Successes of surgical hepatology are in many respects caused by continuous improvement of equipment of liver resection. However discussion of the references containing the description of techniques of resections and necessary for ...
A. Kh. Mustafin +3 more
doaj +1 more source
BioTechniques, 2004 resultant fragments is further destroyed at its unique restriction-purification site. The crude digestion products are ligated in situ to generate a single plasmid containing the two fragments that can be selected for directly. Two of the two-fragment plasmids are then ligated to make a plasmid with a four-fragment insert, and the process is continued ...
Sarah J. Kodumal, Daniel V. Santi
openaire +3 more sources
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Frontiers in Cellular and Infection Microbiology, 2022 Elisa Azuara-Liceaga +14 more
doaj +1 more source
, 2014 Citation: 'ligate' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.L03522 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
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Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source