Results 121 to 130 of about 427,156 (310)

From the RNA-Peptide World: Prebiotic Reaction Conditions Compatible with Lipid Membranes for the Formation of Lipophilic Random Peptides in the Presence of Short Oligonucleotides, and More

Life
Deciphering the origins of life on a molecular level includes unravelling the numerous interactions that could occur between the most important biomolecules being the lipids, peptides and nucleotides.
Augustin Lopez, Antoine Vauchez, Ghinwa Ajram, Anastasiia Shvetsova, Gabrielle Leveau, Michele Fiore, Peter Strazewski   +6 more
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Liver dysfunction induced by bile duct ligation and galactosamine injection alters cardiac protein synthesis

, 2004
Liver disease has been shown to affect the cardiovascular system and may influence cardiac protein metabolism. This hypothesis was tested by measuring rates of cardiac protein synthesis in 2 models of liver disease in rats.
Hunter, R.V., Patel, V., Preedy, V.R., Hunter, R J, Preedy, V R, Baker, A.J., Baker, A J, Patel, V B   +7 more
core   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Preliminary exploration of the feasibility and safety of a novel magnetic ligation ring for hemorrhoid ligation: an experimental study based on canine rectal mucosal ligation procedure

结直肠肛门外科
[Objectives] To preliminarily explore the feasibility and safety of using a novel magnetic ligation ring for hemorrhoid ligation. [Methods] Six adult Labradors were used.
Yang Zhigang, Xu Jiangtao, Liu Chenying, Lou Yamin, Cui Long, He Yongshan   +5 more
doaj   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Complete esophageal obstruction following endoscopic variceal ligation: a case report and literature review

, 2018
Jan Kubovy, Tom D Boswell, Guy Vautier, Malcolm M Arnold Department of Gastroenterology, Hawkes Bay Hospital, Hastings, New ZealandAbstract: Endoscopic variceal ligation (EVL) is an important treatment modality in managing complications of portal ...
Vautier G, Boswell TD, Kubovy J, Arnold MM   +3 more
core  

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

A Prospective Cohort Study in Pediatric Care Rawalpindi to Compare the Orchidopexy with and without Sac Ligation in Terms of Post-Operative Hernia Formation

Life and Science
Objective: To compare the frequency of hernia formation following orchidopexy of clinically palpable undescended testes, regardless of whether the sac was ligated during the procedure. Study Design: Prospective-cohort.
Muhammad Hafeez ur Rehman, Asrar Ahmad, Rizwan Ahmed, Sohail Jabbar, Habib Ur Rehman, Muhammad Sajid Jaral   +5 more
doaj   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source