Results 201 to 210 of about 497,237 (348)

Single‐Nucleus Multi‐Omics Reveals Hypoxia‐Driven Angiogenic Programs and Their Epigenetic Control in Sinonasal Squamous Cell Carcinoma

Advanced Science, EarlyView.
Single‐nucleus multi‐omics profiling of sinonasal squamous cell carcinoma unveils a hypoxia‐driven angiogenic axis. A specific hypoxic tumor subpopulation orchestrates endothelial tip cell differentiation via epigenetically regulated ADM and VEGFA secretion.
Chaelin You, Jaewoo Park, Jung Yeon Jang, Junho Noh, Jaehyun Lee, Geunho Kwon, Myeong Sang Yu, Yoo‐Sam Chung, Seung‐Jun Lee, Keunsoo Kang, Jihwan Park, Ji Heui Kim, Kyuho Kang   +12 more
wiley   +1 more source

Anuria Following Solitary Left Renal Vein Ligation: An Old Surgery Myth Is Rigorously Challenged. [PDF]

Cureus
Onuigbo MA, Balonfentse O.
europepmc   +1 more source

Skeletal Muscle HSF1 Alleviates Age‐Associated Sarcopenia and Mitochondrial Function Decline via SIRT3‐PGC1α Axis

Advanced Science, EarlyView.
Aged HSF1 muscle‐specific knockout mice show deteriorated muscle atrophy and metabolic dysfunction, while active HSF1 overexpression improves muscle function via activating SIRT3 to deacetylate both PGC1α1 and PGC1α4, which boosts mitochondrial function and muscle hypertrophy in a fiber‐type specific manner, and induces FNDC5/Irisin for tissue ...
Jun Zhang, Min Hu, Xia Wu, Mingwei Guo, Ying Ma, Jin Qiu, Siqi Wang, Yuxiang Cao, Yinzhao Zhong, Fangfang Chen, Yiwen Wang, Wei Wei, Yan Lu, Yong Zhang, Junjie Xiao, Zhenji Gan, Cheng Hu, Xinran Ma, Lingyan Xu   +18 more
wiley   +1 more source

Characteristics of Extremely Preterm Infants Undergoing Procedural Closure of Patent Ductus Arteriosus: A Retrospective Cohort Study. [PDF]

Int J Pediatr
Jayakumar N, Uthayakumaran G, Boyd SM, Mervis J, Halliday R, Webb A, Popat H.   +6 more
europepmc   +1 more source

Association of Patent Ductus Arteriosus Ligation With Death or Neurodevelopmental Impairment Among Extremely Preterm Infants

JAMA pediatrics, 2017
D. Weisz, L. Mirea, E. Rosenberg, Maximus Jang, Linh G Ly, Paige Church, E. Kelly, S. Joseph Kim, Amish Jain, P. McNamara, Prakeshkumar Shah   +10 more
semanticscholar   +1 more source

PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites

Advanced Science, EarlyView.
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang, Qian Shen, Yao Lin, Jing Zhu, Xiaolan Zhu, Rui Huang, Yijia Wu, Feiyang Shen, Qian Li, Guopei Zheng, Zhe Zhang, Qian Chu, Junhao Hu, Jianfeng Shen   +13 more
wiley   +1 more source

High-resolution Hi-C profiling of human breast tissues using an optimized protocol for clinical samples. [PDF]

STAR Protoc
Choppavarapu L, Fang K, Eacker S, Langford K, Rader JS, Jin VX.   +5 more
europepmc   +1 more source

Anatomical and electrical remodeling with incomplete left atrial appendage ligation: Results from the LAALA‐AF registry

, 2017
Mohit K. Turagam, Donita Atkins, Matthew Earnest, Randall Lee, Jayant Nath, Ryan Ferrell, Krzysztof Bartuś, Nitish Badhwar, Abdi Rasekh, Jie Cheng, Luigi Di Biase, Andrea Natale, David J. Wilber, Dhanunjaya Lakkireddy   +13 more
openalex   +2 more sources

Chemical Protein Synthesis with the α-Ketoacid-Hydroxylamine Ligation.

Accounts of Chemical Research, 2017
J. Bode
semanticscholar   +1 more source

A Hydrodynamic Bioreactor for High‐Yield Production of Extracellular Vesicles from Stem Cell Spheroids with Defined Cargo Profiling

Advanced Science, EarlyView.
This study harnesses hydrodynamic flows to generate, confine and stimulate stem cell spheroids, enabling the large‐scale production of extracellular vesicles (EVs). This innovative method not only streamlines spheroid formation and subsequent EV release in a single, integrated process, but also ensures the generation of EVs with enhanced biological ...
Solène Lenoir, Elliot Thouvenot, Giacomo Gropplero, Léonie Dec, Damarys Loew, Clotilde Théry, Jose E Perez, Claire Wilhelm   +7 more
wiley   +1 more source