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Native Chemical Ligation and Extended Methods: Mechanisms, Catalysis, Scope, and Limitations
Chemical Reviews, 2019The native chemical ligation reaction (NCL) involves reacting a C-terminal peptide thioester with an N-terminal cysteinyl peptide to produce a native peptide bond between the two fragments. This reaction has considerably extended the size of polypeptides
Vangelis Agouridas +2 more
exaly +2 more sources
Ligation Technologies for the Synthesis of Cyclic Peptides
Chemical Reviews, 2019Cyclic peptides have been attracting a lot of attention in recent decades, especially in the area of drug discovery, as more and more naturally occurring cyclic peptides with diverse biological activities have been discovered.
Xuechen Li
exaly +2 more sources
Serine/Threonine Ligation and Cysteine/Penicillamine Ligation
2022Serine/threonine ligation (STL) and cysteine/penicillamine ligation (CPL) are highly chemo- and regioselective reactions between unprotected peptides with C-terminus salicylaldehyde esters and unprotected peptides with N-terminus serine/threonine or cysteine/penicillamine, which serve as powerful tools for cyclic peptide natural product and chemical ...
Jiamei, Liu, Xuechen, Li
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Subtiligase-Catalyzed Peptide Ligation.
Chemical Reviews, 2020Subtiligase-catalyzed peptide ligation is a powerful approach for site-specific protein bioconjugation, synthesis and semisynthesis of proteins and peptides, and chemoproteomic analysis of cellular N termini.
A. Weeks, J. Wells
semanticscholar +1 more source
Chemoselective Ligation in Glycochemistry
ChemInform, 2004AbstractFor Abstract see ChemInform Abstract in Full Text.
PERI, FRANCESCO, NICOTRA, FRANCESCO
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Pedicle ligation in ovariohysterectomy: an in vitro study of ligation techniques
Journal of Small Animal Practice, 2012ObjectivesLigature failure is an important complication following ovariohysterectomy in the bitch. The aim of this study was to assess the differences between five individual ligation techniques in their ability to attenuate a bulky vascular model.MethodsA vascular model was constructed that enabled the occlusive ability of five different ligation ...
J. P. Bray +4 more
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Angewandte Chemie, 2018
The epitranscriptomic mark N6 -methyladenosine (m6 A) is the most abundant RNA modification in eukaryotic mRNA, but various limitations in currently available m6 A detection methods have precluded routine identification of m6 A marks at the single-site ...
Yu Xiao +5 more
semanticscholar +1 more source
The epitranscriptomic mark N6 -methyladenosine (m6 A) is the most abundant RNA modification in eukaryotic mRNA, but various limitations in currently available m6 A detection methods have precluded routine identification of m6 A marks at the single-site ...
Yu Xiao +5 more
semanticscholar +1 more source
JAMA: The Journal of the American Medical Association, 1970
To the Editor:— While standard textbooks describe in detail the syndrome associated with thrombosis of the renal vein, we have been able to find no report of the consequences of renal veinligation. We were pleasantly surprised by the lack of ill effects of such a procedure in the case reported below. Report of a Case.— A 16-year-old boy was admitted
M. A. Glucksman, E. R. Jennings
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To the Editor:— While standard textbooks describe in detail the syndrome associated with thrombosis of the renal vein, we have been able to find no report of the consequences of renal veinligation. We were pleasantly surprised by the lack of ill effects of such a procedure in the case reported below. Report of a Case.— A 16-year-old boy was admitted
M. A. Glucksman, E. R. Jennings
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Obstetrical & Gynecological Survey, 1972
Postpartum abdominal sterilization by the Pomeroy method or tubal cauterization by laparoscopy are recommended over the procedure of vaginal tubal ligation described by McMaster and Ansari (Obstetrics and Gynecology 38: 44-50. 1971). The abdominal Pomeroy method is quick and laparoscopy requires a shorter hospital stay.
R H, McMaster, A H, Ansari
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Postpartum abdominal sterilization by the Pomeroy method or tubal cauterization by laparoscopy are recommended over the procedure of vaginal tubal ligation described by McMaster and Ansari (Obstetrics and Gynecology 38: 44-50. 1971). The abdominal Pomeroy method is quick and laparoscopy requires a shorter hospital stay.
R H, McMaster, A H, Ansari
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Simultaneous ligation of vein in ligation of large arteries
The American Journal of Surgery, 1931Abstract Consideration of the problem of simultaneous ligation of the companion vein when it is necessary to ligate a large artery has led to a review of the clinical and experimental literature and the presentation of our own experimental results. Review of the clinical literature leads us to believe that: (1) Most surgeons consider the incidence of
Daniel A. Mulvihill +2 more
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