Results 41 to 50 of about 79,379 (295)

Recovery of small plasmid sequences via Oxford Nanopore sequencing.

, 2021
Oxford Nanopore Technologies (ONT) sequencing platforms currently offer two approaches to whole-genome native-DNA library preparation: ligation and rapid.
Judd, Louise M, Wyres, Kelly L, Wick, RR, Holt, Kathryn E, Holt, KE, Wick, Ryan R, Judd, LM, Wyres, KL   +7 more
core   +1 more source

Case Report: Rectal perforation combined with presacral infection following rubber band ligation and sclerotherapy for hemorrhoids

Frontiers in Medicine
BackgroundCurrently, rubber band ligation and injection sclerotherapy represent the first-line therapeutic strategy for grade I–III internal hemorrhoids.
Yanqing Lu, Ziwen Wang, Zhenfu Shi, Zhi Jiang, Li Zhang, Guolian Gan, Zhen Zhou, Hao Wang   +7 more
doaj   +1 more source

The CD200-CD200 receptor inhibitory axis controls arteriogenesis and local T lymphocyte influx.

PLoS ONE, 2014
The role of the CD200 ligand-CD200 receptor (CD200-CD200R) inhibitory axis is highly important in controlling myeloid cell function. Since the activation of myeloid cells is crucial in arteriogenesis, we hypothesized that disruption of the CD200-CD200R ...
Pleunie van den Borne, Tomasz P Rygiel, Ayla Hoogendoorn, Geertje H A Westerlaken, Louis Boon, Paul H A Quax, Gerard Pasterkamp, Imo E Hoefer, Linde Meyaard   +8 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

One-pot ligation protocol for Oxford Nanopore libraries v1

, 2017
This is our ‘one-pot ligation’ protocol for Oxford Nanopore ligation libraries. It benefits from increased recovery of library and faster preparation time by using the Ultra II ligation modulein conjunctionwith the Ultra II end repair/dA-tailing module ...
Josh Quick
core   +1 more source

Development and characterization of rat hindlimb ischemia models mimicking peripheral arterial disease severity

Scientific Reports
Peripheral arterial disease (PAD) is a progressive atherosclerotic disorder that reduces blood flow to the lower extremities, leading to skeletal muscle degeneration, functional decline, and limb loss in advanced stages.
Yingxiang Liang, Connor Mullen, Emma R. Young, Mohamed Zaghloul, Yuhan Guo, Shijie Jin, Madeleine Yang, Jingyu Yan, Xiaochao Xia, Batool Arif, Tiffany Ly, Daniel Li, Theodore Lee, Adam Boukind, Jonathon Blake Schofield, Mohamed A. Zayed, Justin M. Sacks, Xiaowei Li   +17 more
doaj   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Local anaesthesia for haemorrhoidal rubber band ligation reduces immediate post-operative recovery time and use of opioid analgesia

, 2020
BACKGROUND: Haemorrhoidal rubber band ligation (RBL) is a well-established, safe and cost-effective treatment for bleeding haemorrhoids. It is generally well tolerated; however, some patients may require narcotic analgesia or even admission to hospital ...
Kong, J, Behrenbruch, C, Chen, F
core   +1 more source

EARLY METABOLIC DYSFUNCTION AGGRAVATES THE MOTOR AND COGNITIVE CONSEQUENCES OF CAROTID ARTERY LIGATION: IMPACT OF ANTITHROMBOTIC DRUG TREATMENT [PDF]

, 2021
Stroke is a predominant cause of death and disability globally. Extensive evidence support a link between poorly controlled blood glucose, diabetes mellitus, elevated stroke risk, and worsened functional outcomes after stroke.
Ghazi, Alaa
core  

Rapid cardiac ischemia detection with an epicardial graphene probe

Frontiers in Cardiovascular Medicine, 2023
IntroductionIn this study, a new probe was designed to enable electrocardiography of a rotated heart during cardiac surgery when skin electrodes became non-functional.
Grzegorz Suwalski, Marek Galanty, Beata Degórska, Jacek Sterna, Jan Frymus, Mikhal Baranski, Piotr Trębacz, Daniel Janczak, Sandra Lepak-Kuc, Małgorzata Jakubowska   +9 more
doaj   +1 more source