Results 91 to 100 of about 80,787 (394)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

NANOCRYSTALLINE MECHNICALLY ALLOWED MODIFIING LIGATURES FOR PRODUCTION OF CHROMIUM BRONZE

open access: yesЛитьë и металлургия, 2016
Theoretically justified and experimentally confirmed the high efficiency of the technology, based on the reactive mechanical alloying to produce nanocrystalline modifying modifiers and ligatures.
F. G. Lovshenko   +2 more
doaj  

Optimization and evaluation of mouse model construction method for severe periodontitis

open access: yesShanghai Jiaotong Daxue xuebao. Yixue ban
Objective·To investigate an optimal severe periodontitis mouse model by comparing two induction methods: simple ligature and ligature combined with injection of Porphyromonas gingivalis lipopolysaccharide (P.g.
WANG Jiaxuan   +3 more
doaj   +1 more source

Comparison of frictional resistance between passive self-ligating brackets and slide-type low-friction ligature brackets during the alignment and leveling stage

open access: yesJournal of Clinical and Experimental Dentistry, 2019
Background To compare the frictional resistance between passive self-ligating brackets and conventional brackets with low-friction ligature under bracket/archwire and root/bone interface during dental alignment and leveling.
Sandra-Liliana Gómez-Gómez   +5 more
semanticscholar   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Facteurs déterminants le regret après ligature tubaire

open access: yesThe Pan African Medical Journal, 2014
INTRODUCTION: La ligature tubaire peut générer regret. Le but de cette étude est d'étudier le vécu après la stérilisation ainsi que le regret et ses facteurs de risque.
Houssine Boufettal   +2 more
doaj   +1 more source

Revised proposal to encode the Avestan script in the SMP of the UCS [PDF]

open access: yes, 2007
This is a proposal to encode the Avestan script in the international character encoding standard Unicode.
Everson, Michael, Pournader, Roozbeh
core  

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

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