Results 11 to 20 of about 80,787 (394)

Effects of metformin on inflammation, oxidative stress, and bone loss in a rat model of periodontitis. [PDF]

PLoS ONE, 2017
To evaluate the effects of metformin (Met) on inflammation, oxidative stress, and bone loss in a rat model of ligature-induced periodontitis.Male albino Wistar rats were divided randomly into five groups of twenty-one rats each, and given the following ...
Aurigena Antunes de Araújo, Aline de Sousa Barbosa Freitas Pereira, Caroline Addison Carvalho Xavier de Medeiros, Gerly Anne de Castro Brito, Renata Ferreira de Carvalho Leitão, Lorena de Souza Araújo, Paulo Marcos Matta Guedes, Sarah Hiyari, Flávia Q Pirih, Raimundo Fernandes de Araújo Júnior   +9 more
doaj   +6 more sources

Impact of hyperglycemia and treatment with metformin on ligature-induced bone loss, bone repair and expression of bone metabolism transcription factors.

PLoS ONE, 2020
This study evaluated the influence of type 2 diabetes mellitus on bone loss, bone repair and cytokine production in hyperglycemic rats, treated or not with metformin.
Fernando Souza Malta, Roberto Puertas Garcia, Josuel Siqueira Azarias, Geysica Kauane Dos Reis Ribeiro, Tamires Szemereske Miranda, Jamil Awad Shibli, Marta Ferreira Bastos   +6 more
doaj   +2 more sources

Effect of chronic alcohol ingestion on the progression of periodontitis induced in Fisher-344 rats [PDF]

RGO: Revista Gaúcha de Odontologia, 2009
Objective: Understand the effect of chronic alcohol on the progression of periodontitis induced in Fischer-344 rats.Methods: For the study, 22 Fischer-344 rats, two months old were used, divided into groups: alcohol (n=8), ligature (n=7) and control (n=7)
Éder Ricardo Biasoli, Tereza Aparecida Delle Vedove Semenoff, Alex Semenoff Segundo   +2 more
doaj   +2 more sources

Curcumin Attenuates Periodontal Injury via Inhibiting Ferroptosis of Ligature-Induced Periodontitis in Mice

International Journal of Molecular Sciences, 2023
Periodontitis is a chronic infectious disease characterized by the destruction of connective tissue and alveolar bone that eventually leads to tooth loss.
Yawei Wang, Hongbing Lin, Wenxin Huang, Zixian Liu, Zhen Chen, Xuetao Zhao, Tong Ding, W. Qin, Yuqin Shen   +8 more
semanticscholar   +1 more source

Application of Ligature-Induced Periodontitis in Mice to Explore the Molecular Mechanism of Periodontal Disease

International Journal of Molecular Sciences, 2021
Periodontitis is an inflammatory disease characterized by the destruction of the periodontium. In the last decade, a new murine model of periodontitis has been widely used to simulate alveolar bone resorption and periodontal soft tissue destruction by ...
Peiya Lin, Hiromi Niimi, Yujin Ohsugi, Y. Tsuchiya, Tsuyoshi Shimohira, Keiji Komatsu, Anhao Liu, Takahiko Shiba, A. Aoki, T. Iwata, Sayaka Katagiri   +10 more
semanticscholar   +1 more source

NLRP3 regulates alveolar bone loss in ligature‐induced periodontitis by promoting osteoclastic differentiation

Cell Proliferation, 2020
NLRP3 inflammasome is a critical part of the innate immune system and plays an important role in a variety of inflammatory diseases. However, the effects of NLRP3 inflammasome on periodontitis have not been fully studied.
Yuyi Chen, Qiudong Yang, C. Lv, Yue Chen, Wenhua Zhao, Wenlei Li, Hongyu Chen, Hua Wang, Wen-lan Sun, Hua Yuan   +9 more
semanticscholar   +1 more source

Activated STAT3 signaling pathway by ligature-induced periodontitis could contribute to neuroinflammation and cognitive impairment in rats

Journal of Neuroinflammation, 2020
Background Increasing evidence suggests a causal link between periodontitis and cognitive disorders. Systemic inflammation initiated by periodontitis may mediate the development of cognitive impairment.
Yi Hu, Xu Zhang, Jing Zhang, Xinyi Xia, Huxiao Li, C. Qiu, Y. Liao, Huiwen Chen, Zhi-Yuan He, Zhongchen Song, Wei Zhou   +10 more
semanticscholar   +1 more source

Prophylactic Ligature of AV Fistula Prevents High Output Heart Failure after Kidney Transplantation

American Journal of Nephrology, 2020
Background: Arteriovenous (AV) fistulas are considered the gold standard for ensuring safe and long-term vascular access in patients with haemodialysis-dependent end-stage renal disease.
Patrick Hetz, M. Pirklbauer, S. Müller, L. Posch, M. Gummerer, M. Tiefenthaler   +5 more
semanticscholar   +1 more source

Rosuvastatin Prevents the Exacerbation of Atherosclerosis in Ligature-Induced Periodontal Disease Mouse Model

Scientific Reports, 2020
Periodontitis is a local and systemic inflammatory condition and a risk factor of atherosclerosis, but no studies investigated the effect of a statin on atherogenesis affected by severe periodontitis.
J. Suh, S. H. Lee, Zachary Fouladian, Jae Young Lee, Terresa Kim, Mo K. Kang, A. Lusis, K. Boström, R. Kim, N. Park   +9 more
semanticscholar   +1 more source

THE USE OF OXIDES OF NON-FERROUS METALS FOR ECONOMICAL ALLOYING OF STEEL

Литьë и металлургия, 2015
The research is made to compare characteristics of thermodynamic data on restitution of oxides Ni, Mo and W through slag phase and to evaluate experimental data of melting and alloying in superpower arc furnaces.
V. Rimoshevski, D. Ivanov, L. Tribushevski, S. Rimoshevski   +3 more
doaj   +1 more source