Results 191 to 200 of about 80,787 (394)
Advanced Science, EarlyView.Based on a well‐established in vitro directed differentiation model and an integrated analysis of high‐density cell lineage trees (CLTs) and single‐cell transcriptomes, it is demonstrated that many subclones are formed by sub‐CLTs resembling each other in terms of both cell type compositions and topological structures.
Xiaoyu Zhang +14 more
wiley +1 more source
Non‐Invasive Diagnosis of Chronic Myocardial Infarction via Composite In‐Silico‐Human Data Learning
Advanced Science, EarlyView.This study presents a non‐invasive machine learning model to identify infarct regions in the left ventricle using cardiac strain data. By combining rodent‐based simulated data with limited human data, the model achieves high accuracy in predicting infarct size and location without the need for gadolinium contrast agents, offering a promising ...
Rana Raza Mehdi +7 more
wiley +1 more source
CASE OF ERECTILE TUMOUR OF THE ORBIT, CURED BY INFILTRATION WITH THE SOLUTION OF THE LACTATE OF IRON AND PUNCTURE WITH HOT NEEDLES, AFTER THE LIGATURE OF THE CAROTID ARTERY HAD FAILED; [PDF]
Daniel Brainard
openalex +1 more source
ANEURYSM OF THE INNOMINATE ARTERY TREATED BY PROXIMAL LIGATURE [PDF]
, 1934 H. S. Souttar
openalex +1 more source
Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation
Advanced Science, EarlyView.At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao +14 more
wiley +1 more source
NOX2 Contributes to High‐Frequency Outer Hair Cell Vulnerability in the Cochlea
Advanced Science, EarlyView.This study first identifies NOX2 as a differentially expressed gene related to oxidative damage in the apical and basal turns through single‐cell RNA sequencing. NOX2 gene knockout mitigates OHCs damage caused by neomycin and noise and enhances Nrf2 expression and nuclear translocation.
Meihao Qi +16 more
wiley +1 more source