A Phase‐Separated SR Protein Reprograms Host Pre‐mRNA Splicing to Enhance Disease Susceptibility
This study identifies SR30, a splicing factor, as a negative regulator of tomato immunity. During Phytophthora infestans infection, the elevated SR30 forms nuclear condensates to suppress the alternative splicing (AS) of defense‐related genes in a phase separation manner.
Dong Yan+11 more
wiley +1 more source
Experimental orthodontic pain drives anxiety state through the induction of alterations to the neuronal architecture in hippocampus. [PDF]
Que H+8 more
europepmc +1 more source
Molecular mechanism study of self‐assembled M2pep‐Cs NPs/Plerixafor nanoparticles in targeting MΦ reprogramming by regulating the CXCL12–CXCR4 signaling pathway to enhance immune recognition and clearance of GC (Created by BioRender). Abstract Gastric carcinoma (GC) remains a major global health challenge, requiring novel therapeutic approaches.
Qianqian Cao+9 more
wiley +1 more source
Ovarian Pedicle Local Analgesia in Midline versus Flank Cat Ovariectomy. [PDF]
Carbonari A+7 more
europepmc +1 more source
SUCCESSFUL CASE OF LIGATURE OF THE EXTERNAL ILIAC ARTERY, CLOSE TO ITS ORIGIN FROM THE COMMON ILIAC, FOR INGUINAL ANEURISM. [PDF]
WM. Philpot Brookes
openalex +1 more source
Wound infections induce gcFGF8a expression, which subsequently executes direct antimicrobial activity to suppress local infection while simultaneously activating the FGFR4‐mediated ERK/AKT‐mTOR signaling cascade, thereby upregulating HIF1α and enhancing glycolysis. These coordinated actions synergistically promote tissue repair by eliminating pathogens
Ya‐Zhen Hu+6 more
wiley +1 more source
Therapeutic Potential of AgNP-Infused Patches in Periodontal Disease: An Observational Study in Albino Rats. [PDF]
Barik B+6 more
europepmc +1 more source
Two Cases of Aneurism, exhibiting the necessity of a Ligature, both above and below the Tumour [PDF]
Wm. E. Horner
openalex +1 more source
RECURRENT ANEURISM OF THE SUPERFICIAL FEMORAL ARTERY AFTER LIGATURE OF THE EXTERNAL ILIAC, TREATED BY EXCISION OF THE SAC. [PDF]
William Rose
openalex +1 more source