Results 271 to 280 of about 81,649 (382)

Potentiating Cerebral Perfusion Normalizes Glymphatic Dynamics in Systemic Inflammation

open access: yesAdvanced Science, EarlyView.
LPS‐induced systemic inflammation increases glymphatic influx but delays cervical lymphatic drainage, accompanied by AQP4 depolarization and impaired glymphatic clearance. Enhancing cerebral blood flow via the inotropic agent levosimendan effectively restored AQP4 polarization, improving glymphatic flux and amyloid‐β clearance.
Ruoyu Zhao   +9 more
wiley   +1 more source

Establishing a Dual Murine Model to Explore the Interactions Between Diabetes and Periodontitis in Mice. [PDF]

open access: yesInt J Mol Sci
Silva BR   +11 more
europepmc   +1 more source

Single Cell and Spatial Transcriptomics Define a Proinflammatory and Profibrotic Niche After Kidney Injury

open access: yesAdvanced Science, EarlyView.
By integrating single‐cell RNA sequencing and spatial transcriptomics, tenascin C (TNC) is unveiled as a central organizer of the proinflammatory and profibrotic niche in kidney fibrosis. TNC promotes macrophage activation through TLR4/NF‐κB signaling, leading to renal inflammation and fibrosis.
Li Li   +14 more
wiley   +1 more source

Evaluation of Apoptotic Caspase-3 Immunopositivity in Human Model of Asphyxial Death. [PDF]

open access: yesInt J Mol Sci
Del Duca F   +6 more
europepmc   +1 more source

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