Results 321 to 330 of about 80,787 (394)

Attenuated Nuclear Tension Regulates Progerin‐Induced Mechanosensitive Nuclear Wrinkling and Chromatin Remodeling

open access: yesAdvanced Science, EarlyView.
The premature aging‐related progerin leads to defective nuclear morphology and is associated with disrupted molecular coupling between the extranuclear cytoskeleton and lamin‐associated nuclear envelope. It is discovered that progerin expression reduces nuclear tension, forms nuclear wrinkling, and enhances chromatin dynamics, thereby regulating ...
Ji‐Eun Park   +9 more
wiley   +1 more source

Epithelial RANKL Limits Experimental Periodontitis via Langerhans Cells. [PDF]

open access: yesJ Dent Res
Netanely Y   +15 more
europepmc   +1 more source

Stable Pincer Gold(III)‐TADF Emitters with Extended Donor–Acceptor Separation for Efficient Vacuum‐Deposited OLEDs with Operational Lifetime (LT95) up to 3831 h at 1000 cd m−2

open access: yesAdvanced Science, EarlyView.
Novel pincer gold(III)‐TADF (thermally activated delayed fluorescence) emitters with extended π‐distances exhibit small singlet‐triplet energy gaps (ΔEST), efficient reverse intersystem crossing (RISC), enhanced radiative decay rates and improved excitons utilization, leading to efficient electroluminescence.
Hui‐Xing Shu   +4 more
wiley   +1 more source

Experimental Murine Periodontitis Increases Salivary Gland IgA-Producing B Cells Following Oral Dysbiosis. [PDF]

open access: yesMicrobiol Immunol
Nara M   +7 more
europepmc   +1 more source

Ultralow Overpotential in Rechargeable Li–CO2 Batteries Enabled by Caesium Phosphomolybdate as an Effective Redox Catalyst

open access: yesAdvanced Science, EarlyView.
This study represents the first application of a Keggin‐type polyoxometalate, caesium phosphomolybdate (CPM), as a bifunctional redox catalyst for rechargeable Li–CO2 batteries. CPM significantly reduced the potential gap between discharge and charge reactions to 0.67 V, outperforming most reported catalysts. It also exhibited a high discharge capacity
Mahsa Masoudi   +9 more
wiley   +1 more source

Engineered Cas12j‐8 is a Versatile Platform for Multiplexed Genome Modulation in Mammalian Cells

open access: yesAdvanced Science, EarlyView.
Engineered through structure‐guided protein engineering, enCas12j‐8 significantly enhances the editing efficiency of compact Cas12j‐8 while maintaining high specificity. It enables efficient multiplexed genome editing and base editing using a single crRNA array, demonstrating broad applicability and therapeutic potential in genome engineering ...
Ru Meng   +14 more
wiley   +1 more source

Animal models of oral infectious diseases. [PDF]

open access: yesFront Oral Health
Li J   +7 more
europepmc   +1 more source

Mechanical Stress Induced NOX2 Promotes Endothelial Dysfunction in Ventilator‐Induced Lung Injury: Potential Treatment with Quercetin

open access: yesAdvanced Science, EarlyView.
Abnormal mechanical stretch induced by mechanical ventilation (MV) disrupts endothelial junctions via the NOX2/ROS/CaMKII/ERK1/2 axis both in human aortic endothelial cells (HAECs) in vitro and in ventilator‐induced lung injury (VILI) in mice. Quercetin, an antioxidant predicted to bind to NOX2, can effectively prevent mechanical stretch‐induced ...
Tao Jiang   +8 more
wiley   +1 more source

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