Results 331 to 340 of about 81,649 (382)

The Effects of Temporary Interruption of Hepatic Blood Circulation. [PDF]

open access: yesCureus
Turmanidze T   +8 more
europepmc   +1 more source

Src Reduces Neutrophil Extracellular Traps Generation and Resolves Acute Organ Damage

open access: yesAdvanced Science, EarlyView.
Src reduces neutrophil extracellular traps (NETs) generation and resolves acute organ damage. Src directly activates RAF1 by regulating phosphorylation at the Ser 621 site and mediates the RAF/MEK/ERK pathway, thereby affecting the intracellular ROS production. Alternatively, Src activates the RAF1/MEK/ERK pathway by mediating PKC phosphorylation.
Guotao Lu   +18 more
wiley   +1 more source

Onion‐Mitochondria Inhibit Lipopolysaccharide‐Induced Acute Lung Injury by Shaping Lung Macrophage Mitochondrial Function

open access: yesAdvanced Science, EarlyView.
Proposed model of orally administered onion mitochondria (O‐Mit) uptake by lung macrophages and fuse with macrophage mitochondria (M‐Mit). This fusion reprograms the metabolism of dysfunctional M‐Mit in lipopolysaccharide‐induced murine acute lung injury by modulating dynamin‐related protein 1 (DRP1) phosphorylation and cardiolipin peroxidation ...
Qingbo Xu   +13 more
wiley   +1 more source

Ovarian Pedicle Local Analgesia in Midline versus Flank Cat Ovariectomy. [PDF]

open access: yesVet Med Sci
Carbonari A   +7 more
europepmc   +1 more source

Lactate Activates the HCAR1/β‐Arrestin2/PP2A Signaling Axis to Mediate STAT1/2 Dephosphorylation and Drive Osteosarcoma Progression

open access: yesAdvanced Science, EarlyView.
In the present study, it is found that in osteosarcoma, lactate‐activated HCAR1 promotes β‐arrestin 2 translocation from cytoplasm to nucleus. In the nucleus, β‐arrestin 2 recruits PP2A to the activated STAT1/2 dimers, mediating STAT1/2 dephosphorylation and inhibiting the transcription of downstream anti‐oncogenes to promote OS progression.
Zhitao Han   +26 more
wiley   +1 more source

Effects of aged garlic extract on experimental periodontitis in mice. [PDF]

open access: yesBiomed Rep
Kuang C   +6 more
europepmc   +1 more source

Tip efficiency of a customized lingual appliance: Performance of wires with two different ligatures. [PDF]

open access: yesEur J Oral Sci
Drago S   +6 more
europepmc   +1 more source

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