Results 51 to 60 of about 39,294 (296)
Facteurs déterminants le regret après ligature tubaire
The Pan African Medical Journal, 2014 INTRODUCTION: La ligature tubaire peut générer regret. Le but de cette étude est d'étudier le vécu après la stérilisation ainsi que le regret et ses facteurs de risque.
Houssine Boufettal +2 more
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Клінічна хірургія, 2020 Objective. To improve the efficacy of endoscopic hemostasis for the ulcer gastro-duodenal hemorrhage, using high-frequency biological welding electro-ligature. Materials and methods.
Ya. P. Feleshtynskyi +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Patient Safety, 2019 It takes less than five minutes and 18 inches from the ground for a person to self-asphyxiate from hanging.1 According to the American Foundation for Suicide Prevention (AFSP), suicide is currently the 10th leading cause of death in the United States and
Christopher Mamrol +2 more
doaj +2 more sources
Generation, structure and properties of the modified welding seams
Литьë и металлургия, 2018 Preparation, structure and properties of modified welds by using electrodes with coatings, which contain, along with classical components, a modifying ligature.
F. G. Lovshenko, A. I. Khabibulin
doaj +1 more source
Brain Sciences, 2020 Background: Periodontal disease (PD) is a risk factor for systemic diseases, including neurodegenerative diseases. The role of the local and systemic inflammation induced by PD in neuroinflammation currently remains unclear.
Daisuke Furutama +13 more
doaj +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
An autopsy study of death due to Suicidal Hanging – 264 cases
Egyptian Journal of Forensic Sciences, 2016 The present study was carried out between 2010 and 2013, a total of 7968 Autopsies were conducted of which 3.31% (n – 264) cases were deaths due to hanging. The most preferred ligature materials were Stole (n – 79) and Bed spread/Sari (n – 68). In 88% of
Dinesh Rao
doaj +1 more source