Results 71 to 80 of about 39,294 (296)

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Effect of obesity on alveolar bone loss in experimental periodontitis in Wistar rats

Journal of Applied Oral Science, 2012
Obesity has been linked to higher inflammatory status and periodontal breakdown. OBJECTIVE: The purpose of this study was to investigate the effect of obesity on alveolar bone loss in experimental periodontitis in rats.
Giliano Nicolini Verzeletti, Eduardo José Gaio, Daniele Sigal Linhares, Cassiano Kuchenbecker Rösing   +3 more
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Pirfenidone Inhibits Alveolar Bone Loss in Ligature-Induced Periodontitis by Suppressing the NF-κB Signaling Pathway in Mice [PDF]

, 2023
Zijiao Zhang, Juhan Song, Seung‐Hee Kwon, Zhao Wang, Suk‐Gyun Park, Xianyu Piao, Je‐Hwang Ryu, Nacksung Kim, Ok-Su Kim, Sun-Hun Kim, Jeong‐Tae Koh   +10 more
openalex   +1 more source

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source

Chronic stress associated to contraceptives use on the progression of ligature-induced periodontitis in rats

Revista de Odontologia da UNESP
Introduction Contraceptives are widely used by women in much of the world. The stress associated with their use can lead adverse responses in the body.
Débora Prado MARTINS, Tereza Aparecida Delle Vedove SEMENOFF, Álvaro Henrique BORGES, Natalino Francisco da SILVA, Alex SEMENOFF-SEGUNDO   +4 more
doaj   +1 more source

Surgical sterilization of free-ranging capybaras (Hydrochoerus hydrochaeris): “Passos Nunes” uterine horn ligature [PDF]

, 2022
Fernanda Battistella Passos Nunes, Fabiana Morse Gosson Jorge, Mariana Passos Nunes, Alexandre Zanetti Nunes, Pedro Nacib Jorge‐Neto, Antônio Chaves de Assís Neto, Marcelo B. Labruna, Cristiane Schilbach Pizzutto   +7 more
openalex   +1 more source

Monocyte LOXHD1 and RHOB Expression Predictive of Progressive Systemic Sclerosis–Associated Interstitial Lung Disease

Arthritis Care &Research, EarlyView.
Objective A leading cause of death among patients with scleroderma (SSc), interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M. Padilla, Robert Lafyatis, Kevin F. Gibson, Christina Morse, Eleanor Valenzi, Xiaoping Chen, Xiaoyun Li, Yanwu Zhao, Yongseok Park, Dana Ascherman, Jonathan Minden, Robyn Domsic, Yingze Zhang, Daniel J. Kass   +13 more
wiley   +1 more source

Continuous Feed Ligature Carrier

Experimental Biology and Medicine, 1956
In experiments in our laboratory, where perfusinos were made on small animals, ligatures were made around the aorta in 4 places. Since a rather large number of operations were to be performed, a faster method was sought to make these ties. The instrument shown in Fig. 1 was made.
openaire   +2 more sources

A Case of Perforating Wound of the Abdomen: In which the Superior Mesenteric Vein was Wounded: Ligature of Vein: Lavage of Abdomen: Transfusion: Recovery [PDF]

, 1897
A. W. M. Robson
openalex   +1 more source