Results 81 to 90 of about 80,787 (394)

“Do Not Kill Guinea Pig before Setting up Apparatus”: The Kymograph's Lost Educational Context [PDF]

open access: yes, 2016
The objects of science education are transformed, degraded and disappeared for many reasons, and sometimes take other things with them when they go. This close reading of an undergraduate physiology laboratory report demonstrates how the kymograph was ...
Kwan, Alistair Marcus
core   +2 more sources

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

Experiments with Ligatures [PDF]

open access: yesThe American Journal of the Medical Sciences
n ...
openaire   +3 more sources

Ligature-Induced Experimental Peri-Implantitis—A Systematic Review

open access: yesJournal of Clinical Medicine, 2018
This systematic review sought to analyze different experimental peri-implantitis models, their potential to induce marginal bone resorption (MBR) and the necessity of bacteria for bone loss to occur in these models. An electronic search in PubMed/Medline,
David Reinedahl   +4 more
semanticscholar   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

A Scale and Rotation Invariant Urdu Nastalique Ligature Recognition Using Cascade Forward Backpropagation Neural Network

open access: yesIEEE Access, 2019
In the emerging age of technologies, machines are becoming more and more skilled and capable just like humans. Despite the fact that machines do not have their own intelligence, but still due to advancement in Artificial Intelligence (AI), machines are ...
Khawaja Ubaid Ur Rehman, Y. Khan
semanticscholar   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

Biological Activity of Copaiba in Damage to the Alveolar Bone in a Model of Periodontitis Induced in Rats

open access: yesMolecules, 2022
Several studies have investigated the effects of natural products in the treatment of diseases. Traditional Amazonian populations commonly use copaiba due to its well-known anti-inflammatory, antibacterial, and healing properties. In this study, we aimed
Vinicius Ruan Neves dos Santos   +13 more
doaj   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Two Stream Deep Neural Network for Sequence-Based Urdu Ligature Recognition

open access: yesIEEE Access, 2019
Urdu text is a complex cursive script and poses a challenge for recognition by OCR systems due to its large number of ligatures and cursive style. In literature, several techniques have been proposed to recognize Urdu ligatures.
Syed Yasser Arafat, M. Iqbal
semanticscholar   +1 more source

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