Results 101 to 110 of about 687,578 (301)
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Converting water adsorption and capillary condensation in useable forces with simple porous inorganic thin films [PDF]
This work reports an innovative humidity driven actuation concept based on Bangham effect using simple nanoporous sol-gel silica thin films as humidity responsive materials.
Boudot, Mickael +2 more
core +3 more sources
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa +2 more
wiley +1 more source
A light-driven artificial flytrap
Stimuli-responsive materials are commonly used in autonomous systems, whilst it is challenging to power them in a programmable manner. Here, Waniet al. use an optical fibre to control the shape of light-responsive liquid-crystal elastomers, which allow ...
Owies M. Wani, Hao Zeng, Arri Priimagi
doaj +1 more source
Stimuli-Responsive Polymer Brushes for Flow Control through Nanopores
Responsive polymers attached to the inside of nano/micro-pores have attracted great interest owing to the prospect of designing flow-control devices and signal responsive delivery systems.
Shashishekar P. Adiga, Donald W. Brenner
doaj +1 more source
Novel multifunctional materials based on ionic liquids: on demand micro-valve actuation for lab-on-a-chip applications [PDF]
We present the fabrication, characterization and performance as a micro-valve of four novel materials, ionogels, consisting in a polymeric structure with benzospiro-pyran units and phosphonium based ionic liquids. Each inonogel is photopolymerised in the
Benito-Lopez, Fernando +3 more
core
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Intercompartmental communication in senescence
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz +3 more
wiley +1 more source
Light-Responsive and Antibacterial Graphenic Materials as a Holistic Approach to Tissue Engineering
While the continuous development of advanced bioprinting technologies is under fervent study, enhancing the regenerative potential of hydrogel-based constructs using external stimuli for wound dressing has yet to be tackled. Fibroblasts play a significant role in wound healing and tissue implants at different stages, including extracellular matrix ...
Ferreras, Andrea +9 more
openaire +6 more sources

