Results 41 to 50 of about 307,221 (264)
Long-Tailed Object Detection for Multimodal Remote Sensing Images
With the rapid development of remote sensing technology, the application of convolutional neural networks in remote sensing object detection has become very widespread, and some multimodal feature fusion networks have also been proposed in recent years ...
Jiaxin Yang +4 more
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Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Suprema of compound Poisson processes with light tails
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
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Background Sheep have developed the ability to store fat in their tails, which is a unique way of reserving energy to survive a harsh environment. However, the mechanism underlying this adaptive trait remains largely unsolved.
Zhangyuan Pan +15 more
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Attraction to artificial light at night (ALAN) poses a threat to many fledgling seabirds leaving their nests for the first time. In Hawai'i, fledgling wedge-tailed shearwaters disoriented by lights may become grounded due to exhaustion or collision ...
Jennifer Urmston +2 more
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Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Log-concavity and log-convexity play a key role in various scientific fields, especially in those where the distinction between exponential and non-exponential distributions is necessary for inferential purposes.
Alex Karagrigoriou +3 more
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Light tails: Gibbs conditional principle under extreme deviation
Let $X_{1},..,X_{n}$ denote an i.i.d. sample with light tail distribution and $S_{1}^{n}$ denote the sum of its terms; let $a_{n}$ be a real sequence\ going to infinity with $n.$\ In a previous paper (\cite{BoniaCao}) it is proved that as $n\rightarrow\infty$, given $\left(S_{1}^{n}/n>a_{n}\right) $ all terms $X_{i_{\text{}}}$ concentrate around $a_{
Broniatowski, Michel, Cao, Zhansheng
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