Results 51 to 60 of about 307,221 (264)
Light tailed asymptotics in an unreliable $M/G/1$ retrial queue [PDF]
Theory of Probability and Mathematical Statistics, 2013 Summary: We consider the standard unreliable \( M/G/1\) retrial queuing system with active and passive breakdowns. The explicit expressions of the probability generating functions of distribution of server state and orbit size are well known from early works.
openaire +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
EFFECTS OF FEEDING SYSTEM AND BREED ON LAMB PRODUCTIVE AND CARCASS CHARACTERISTICS IN THE SOUTH MEDITERRANEAN REGION [PDF]
Poljoprivreda, 2015 The objective of this study was to evaluate the effect of feeding regimes and breed type on growth, non-carcass components and carcass characteristics of light lambs. Twenty four light lambs from the rustic fat-tailed Barbarine (BB) breed and 21 from the
Naziha Atti +2 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
On suprema of Lévy processes with light tails
Stochastic Processes and their Applications, 2010 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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Light-tailed asymptotics of GI/G/1-type Markov chains
Journal of Industrial & Management Optimization, 2017 This paper studies the light-tailed asymptotics of the stationary distribution of the GI/G/1-type Markov chain. We consider three cases:(ⅰ) the tail decay rate is determined by a certain parameter \begin{document}$\theta$\end{document} associated with the transition block matrices \begin{document}$\{\boldsymbol{A}(k);k=0,\pm1,\pm2,\dots\}$\end ...
Tatsuaki Kimura +2 more
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Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
International Journal for Parasitology: Parasites and Wildlife, 2020 Uromastyx is a genus of the herbivorous agamid lizards, also known as spiny-tailed lizards or mastigures, which are found in parts of Africa and the Middle East.
Rie Kubota +4 more
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