In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li+5 more
wiley +1 more source
Non-genetic neuromodulation with graphene optoelectronic actuators for disease models, stem cell maturation, and biohybrid robotics. [PDF]
Molokanova E+19 more
europepmc +1 more source
Workflow of a high‐throughput technology for epigenotyping of differentially methylated CpGs in specific regions of the genome. The protocol works with small amounts of DNA extracted from blood or semen. The protocol consists of both enzymatic conversion of unmethylated cytosines and capture by hybridization with a custom panel.
Nathalie Iannuccelli+4 more
wiley +1 more source
Flat-panel laser displays through large-scale photonic integrated circuits. [PDF]
Shi Z+20 more
europepmc +1 more source
Osmotic pressure‐induced calcium response states
Acute hypotonic stress triggers distinct calcium response patterns in HEK293T cells. These signals originate from the endoplasmic reticulum via RyR2 and propagate to neighboring cells through gap junctions. This result highlights a novel calcium‐dependent mechanism underlying the intracellular and intercellular response to osmotic pressure.
Zidan Gao+2 more
wiley +1 more source
“Made To Be Given”: Generosity as Methodology in Arthur Amiotte’s Collaborations
Julia Hamer-Light
doaj +1 more source
The combined 410nm and infrared light effectively suppresses bacterial survival under realistic conditions. [PDF]
Stangl M, Verma DK, Martinez A, Kim YH.
europepmc +1 more source
Astronomical observations relating to the construction of the heavens, arranged for the purpose of a critical examination, the result of which appears to throw some new light upon the organization of the celestial bodies [PDF]
William Herschel
openalex +1 more source
The cochaperone BAG3 promotes the stabilization of p53 under heat stress conditions
Under heat stress, BAG3 translocates to the nucleus and forms a complex with Hsp70 and p53, thereby promoting p53 stabilization and enhancing its transcriptional activity. These findings suggest that BAG3 functions as a cochaperone that supports p53‐mediated stress responses in cooperation with Hsp70.
Ngoc Nguyen Thi Minh+2 more
wiley +1 more source