Central Dysmyelination in SSADH‐Deficient Humans and Mice
ABSTRACT Objectives Succinic semialdehyde dehydrogenase deficiency (SSADHD) is an inherited metabolic disorder characterized by an accumulation of γ‐aminobutyric (GABA). In addition to its synaptic role as an inhibitory neurotransmitter, GABA also plays an important role in myelination.
Itay Tokatly Latzer +11 more
wiley +1 more source
Reduction of crayfish activity and light avoidance in response to artificial light at night. [PDF]
Boyle K, Zagar A, Stewart C, Davis J.
europepmc +1 more source
ABSTRACT Objective Prognostication of disease course and prediction of treatment response in multiple sclerosis is an unmet need. We compared the performance of serum neurofilament light chain Z scores (age‐ and BMI‐adjusted) with absolute concentrations for the prediction of response to disease‐modifying therapy.
Maximilian Einsiedler +43 more
wiley +1 more source
Carbon metabolism shapes FtsZ levels and cell division in the cyanobacterium Anabaena PCC 7120. [PDF]
Ran WS, Zeng X, Zhang CC.
europepmc +1 more source
The rs10191329 Risk Allele Is Associated With Pronounced Retinal Layer Atrophy in Multiple Sclerosis
ABSTRACT Objective To investigate whether the rs10191329 risk allele in the DYSF–ZNF638 locus, which is implicated in central nervous system resilience rather than immune‐mediated pathology, is associated with retinal layer thinning, a biomarker of neuroaxonal damage in relapsing multiple sclerosis (RMS). Methods From a prospective observational study,
Gabriel Bsteh +22 more
wiley +1 more source
A new method for correcting the refraction angle of starlight under the conditions of 0-[Formula: see text] zenith distance and 0-200 km observation height. [PDF]
Yu D, Wang Y, Huang Z, Liu X.
europepmc +1 more source
Coherent detector for the non-separability measurement of vectorial structured light. [PDF]
Liang Y +13 more
europepmc +1 more source
Installation of cationic phosphorus on dimethyldihydropyrene photoswitches: expanding the atomic repertoire towards far-red photoswitching in water. [PDF]
Maity ML +3 more
europepmc +1 more source
Combination LIGHT overexpression and checkpoint blockade disrupts the tumor immune environment impacting colorectal liver metastases. [PDF]
Keenan BP +13 more
europepmc +1 more source

