Durable B‐Cell Impairment While Sparing IgA B Cells After Ocrelizumab Therapy in Multiple Sclerosis
ABSTRACT Objectives Ocrelizumab (OCR), a humanized anti‐CD20 monoclonal antibody, is highly efficient in relapsing–remitting multiple sclerosis (RR‐MS). We assessed early cellular B‐cell profiles in patients prior to OCR treatment, on OCR treatment, and after 15 months of therapy discontinuation.
Alexandra Garcia+20 more
wiley +1 more source
Defective states of Hermite-Gaussian modes for long-distance image transmission and high-capacity encoding. [PDF]
Zhang Z+10 more
europepmc +1 more source
On the magnetization of light and the illumination of magnetic lines of force
Michael Faraday+2 more
openalex +1 more source
Digital Activity Markers in Chronic Inflammatory Demyelinating Polyneuropathy
ABSTRACT Objective To evaluate the utility of smartwatch and smartphone‐based activity metrics for assessing disease severity and quality of life in patients with chronic inflammatory demyelinating polyneuropathy (CIDP). Methods In the electronic monitoring of disease activity in patients with CIDP (EMDA‐CIDP) trial, we performed a prospective ...
Lars Masanneck+15 more
wiley +1 more source
Impacts of Changing Winters on Lake Ecosystems Will Increase With Latitude. [PDF]
Ozersky T, Poste A, Rautio M, Leu E.
europepmc +1 more source
Multimodal Autonomic Biomarkers Predict Phenoconversion in Pure Autonomic Failure
ABSTRACT Background Pure autonomic failure (PAF) presents with autonomic failure without other neurological features. A third develop central neurological features, fulfilling criteria for multiple system atrophy (MSA) and Lewy body diseases (LBD), including Parkinson's disease and Dementia with Lewy bodies.
S. Koay+12 more
wiley +1 more source
Dark-responsive BGH2 and light-responsive BPG4: Taming the GLK1/2 master transcription factors for etioplast and chloroplast homeostasis. [PDF]
Wang J.
europepmc +1 more source
Central Dysmyelination in SSADH‐Deficient Humans and Mice
ABSTRACT Objectives Succinic semialdehyde dehydrogenase deficiency (SSADHD) is an inherited metabolic disorder characterized by an accumulation of γ‐aminobutyric (GABA). In addition to its synaptic role as an inhibitory neurotransmitter, GABA also plays an important role in myelination.
Itay Tokatly Latzer+11 more
wiley +1 more source
Effect of Fluence Rate on Tumor Tissue Damage in IRDye700DX-Based Photoimmunotherapy. [PDF]
Yamashita S+3 more
europepmc +1 more source