Results 81 to 90 of about 4,739,194 (334)
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Superstring action in AdS_5 x S^5: kappa symmetry light cone gauge
, 2000 As part of program to quantize superstrings in AdS_5 x S^5 background in light cone approach we find the explicit form of the corresponding Green-Schwarz action in fermionic light-cone kappa-symmetry gauge.
A. A. Tseytlin +54 more
core +1 more source
Light-front quantization with the light cone gauge [PDF]
Canadian Journal of Physics, 2016 The Dirac procedure for dealing with constraints is applied to the quantization of gauge theories on the light front. The light cone gauge is used in conjunction with the first-class constraints that arise and the resulting Dirac brackets are found. These gauge conditions are not used to eliminate degrees of freedom from the action prior to applying ...
McKeon, D.G.C., Zhao, Chenguang
openaire +2 more sources
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Neuron, 2019 While rods in the mammalian retina regenerate rhodopsin through a well-characterized pathway in cells of the retinal pigment epithelium (RPE), cone visual pigments are thought to regenerate in part through an additional pathway in Müller cells of the ...
Ala Morshedian +10 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
On Exact Supersymmetry in DLCQ [PDF]
, 1998 In recent years a supersymmetric form of discrete light-cone quantization (hereafter `SDLCQ') has emerged as a very powerful tool for solving supersymmetric field theories.
Antonuccio +9 more
core +3 more sources
High energy QCD at NLO: from light-cone wave function to JIMWLK evolution [PDF]
, 2016 A bstractSoft components of the light cone wave-function of a fast moving projectile hadron is computed in perturbation theory to the third order in QCD coupling constant.
M. Lublinsky, Y. Mulian
semanticscholar +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source