Results 101 to 110 of about 2,354,988 (346)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Principal Component Analysis of RR Lyrae light curves

open access: yes, 2004
In this paper, we analyze the structure of RRab star light curves using Principal Component Analysis. We find this is a very efficient way to describe many aspects of RRab light curve structure: in many cases, a Principal Component fit with 9 parameters ...
H. Mariani   +8 more
core   +3 more sources

Light Curves of Supernovae [PDF]

open access: yesInternational Astronomical Union Colloquium, 1996
Although emerging from a range of progenitor stars and the product of different explosion mechanisms the light curves of the various supernova types are shaped mainly by radioactive power. Core-collapse supernovae have in addition early peaks from shock breakout with a subsequent cooling phase and massive extended stars a recombination (plateau) phase.
openaire   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Three Stages in Evolution of the Object Th4-4

open access: yesGalaxies
The results of observations of the object Th4-4 in 1970–2024 showed that during this period the object went through several stages, when its characteristics corresponded to different classes of objects: Be star, symbiotic star and planetary nebula ...
Lyudmila Kondratyeva   +5 more
doaj   +1 more source

ECLIPSING BINARY STARS : LIGHT CURVE MODELS AND SOFTWARE

open access: yesOdessa Astronomical Publications, 2017
The importance of studying Eclipsing Binary Stars for the determination of fundamental stellar data is sketched. The eclipsing binaries, originally classified phenomenologically, are now understood on the basis of much firmer physics and the improved ...
P. G. Niarchos
doaj   +1 more source

The Optical SN 2012bz Associated with the Long GRB 120422A

open access: yes, 2012
The association of Type Ic SNe with long-duration GRBs is well established. We endeavor, through accurate ground-based observational campaigns, to characterize these SNe at increasingly high redshifts.
A. J. Castro-Tirado   +107 more
core   +2 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

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