Results 111 to 120 of about 2,259,814 (348)

ECLIPSING BINARY STARS : LIGHT CURVE MODELS AND SOFTWARE

Odessa Astronomical Publications, 2017
The importance of studying Eclipsing Binary Stars for the determination of fundamental stellar data is sketched. The eclipsing binaries, originally classified phenomenologically, are now understood on the basis of much firmer physics and the improved ...
P. G. Niarchos
doaj   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Three Stages in Evolution of the Object Th4-4

Galaxies
The results of observations of the object Th4-4 in 1970–2024 showed that during this period the object went through several stages, when its characteristics corresponded to different classes of objects: Be star, symbiotic star and planetary nebula ...
Lyudmila Kondratyeva, Eduard Denissyuk, Saule Shomshekova, Inna Reva, Gauhar Aimanova, Maxim Krugov   +5 more
doaj   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

The Light Curve Analysis of AW Cam [PDF]

Journal of Astronomy and Space Sciences, 1995
The α Lyrae-type eclipsing binary AW Cam was observed photoelectrically in three wavelength regions. The obtained UBV light curves of AW Cam were analyzed with two separate modes (mode 2 for detached systems and mode 5 for semi-detached ones) of the ...
Chun-Hwey Kim, Wonyong Han
doaj  

Export Diversification Curve in Light of the Ricardian Model

Gospodarka Narodowa. The Polish Journal of Economics, 2017
In this paper we identify the determinants of export diversification from the perspective of the Ricardian model with many goods. According to this approach, the export diversification of a country can be regarded as an outcome of two effects: a relative
Andrzej Cieślik
doaj   +1 more source

Modelling the light-curve of KIC 12557548b: an extrasolar planet with a comet like tail

, 2013
An object with a very peculiar light-curve was discovered recently using Kepler data. Authors argue that this object may be a transiting disintegrating planet with a comet like dusty tail. We calculate the light-curves of stars with such planets and take
Batalha, Bisikalo, Borucki, Bourrier, Brogi, Budaj, Budaj, Burrows, Carroll, Claret, Clover, Cohen, Cuntz, Deirmendjian, Dorschner, Faigler, Galan, Guillot, Guinan, Gurdemir, Hoard, Hubbard, Ip, J. Budaj, Jackson, Jia, Johnson, Jäger, Knutson, Kocifaj, Krejčová, Kuchar, Lanza, Leadbeater, Lecavelier Des Etangs, Lecavelier Des Etangs, Lopez, L’eger, Mandel, Miller, Mura, Muthumariappan, Ordal, Perez-Becker, Rappaport, Rucinski, Sadakane, Sekanina, Shi, Shkolnik, Shkolnik, Southworth, Stellingwerf, Tian, Valencia, Vidal-Madjar, Vidal-Madjar, Vourlidas, Yelle   +58 more
core   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source