Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Hubble Residuals of Nearby Type Ia Supernovae Are Correlated with Host Galaxy Masses
From Sloan Digital Sky Survey u'g'r'i'z' imaging, we estimate the stellar masses of the host galaxies of 70 low redshift SN Ia (0.015 < z < 0.08) from the hosts' absolute luminosities and mass-to-light ratios.
Abazajian +53 more
core +1 more source
Predicted Light Curves for a Model of Solar Eruptions [PDF]
Katharine K. Reeves, T. G. Forbes
openalex +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
An Alternate Light Curve Solution of AR Lacertae [PDF]
Photoelectric UBV light curves of AR Lacertae made in one season during 1981-82 are presented. Although the shape of the light curves in the outside eclipses show a strong distortion, the scatter of observations as well as phase coverage are better than ...
Hong Suh Park
doaj
Wavelet-based filter methods to detect small transiting planets in stellar light curves [PDF]
S. Grziwa, M. Pätzold
openalex +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
A FURTHER INVESTIGATION OF APPARENT PERIODICITIES AND THE ROTATIONAL STATE OF COMET 103P/HARTLEY 2 FROM COMBINED COMA MORPHOLOGY AND LIGHT CURVE DATA SETS [PDF]
Matthew M. Knight +3 more
openalex +1 more source
Effects of accumulated temperature on growth curve ofGynostemma pentaphyllumstem and leaf under the conditions of Simulated light under the forest [PDF]
Chunyao Dun +4 more
openalex +1 more source

