Results 121 to 130 of about 8,054,126 (389)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Classification of Variable Star Light Curves with Convolutional Neural Network

Galaxies
The classification of variable stars is essential for understanding stellar evolution and dynamics. With the growing volume of light curve data from extensive surveys, there is a need for automated and accurate classification methods. Traditional methods
Almat Akhmetali, Timur Namazbayev, Gulnur Subebekova, Marat Zaidyn, Aigerim Akniyazova, Yeskendyr Ashimov, Nurzhan Ussipov   +6 more
doaj   +1 more source

Photometric Light Curve Analysis of ET Leo

Zanco Journal of Pure and Applied Sciences, 2019
In this work, the short period system named (ET Leo) have been chosen to be analyzed with B , V and R light curves with the Wilson-Devinney code and the results of orbital parameters of the system were obtained and compared with those obtained from ...
Aven M. Hamedamen, Ismail M. Murad
doaj   +1 more source

Evidence for the disintegration of KIC 12557548 b [PDF]

, 2012
Context. The Kepler object KIC 12557548 b is peculiar. It exhibits transit-like features every 15.7 hours that vary in depth between 0.2% and 1.2%. Rappaport et al.
C. U. Keller, Claret, Draine, Gelman, Hastings, Henyey, I. A. G. Snellen, Lamers, M. A. Kenworthy, M. Brogi, M. de Juan Ovelar, M. Min, R. J. de Kok, Rappaport   +13 more
core   +3 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Classification of Exoplanetary Light Curves Using Artificial Intelligence

AI
In this article, we propose a robust star classification methodology leveraging light curves collected from 15 datasets within the Kepler field in the visible optical spectrum.
Leticia Flores-Pulido, Liliana Ibeth Barbosa-Santillán, Ma. Teresa Orozco-Aguilera, Bertha Patricia Guzman-Velázquez   +3 more
doaj   +1 more source

Assessing low-light cameras with photon transfer curve method [PDF]

Journal of Innovative Optical Health Sciences, 2016
Low-light camera is an indispensable component in various fluorescence microscopy techniques. However, choosing an appropriate low-light camera for a specific technique (for example, single molecule imaging) is always time-consuming and sometimes ...
Luchang Li, Mengting Li, Zhaoning Zhang, Zhen-Li Huang   +3 more
doaj   +1 more source

The optical light curve of GRB 970228 refined

, 1997
We present the R and V light curves of the optical counterpart of GRB 970228. A critical analysis of all the available data is made in light of the results achieved in the recent GRB Symposium held in Huntsville and by considering the latest information ...
A. Guarnieri, A. Piccioni, Bartolini, C. Bartolini, Fox, Fruchter, Fruchter, Galama, Groot, Guarnieri, Margon, Metzger, N. Masetti, Pedichini, Sahu, van Paradijs   +15 more
core   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

TLW: A Real-Time Light Curve Classification Algorithm for Transients Based on Machine Learning

Universe
The real-time light curve classification of transients is helpful in searching for rare transients. We propose a new algorithm based on machine learning, namely the Temporary Convective Network and Light Gradient Boosting Machine Combined with Weight ...
Mengci Li, Chao Wu, Zhe Kang, Chengzhi Liu, Shiyu Deng, Zhenwei Li   +5 more
doaj   +1 more source