Results 131 to 140 of about 2,321,585 (305)
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
A FURTHER INVESTIGATION OF APPARENT PERIODICITIES AND THE ROTATIONAL STATE OF COMET 103P/HARTLEY 2 FROM COMBINED COMA MORPHOLOGY AND LIGHT CURVE DATA SETS [PDF]
Matthew M. Knight +3 more
openalex +1 more source
Spectral Modeling of Flares in Long-term Gamma-Ray Light Curve of PKS 0903-57 [PDF]
Sandeep Kumar Mondal +3 more
openalex +1 more source
Workflow of a high‐throughput technology for epigenotyping of differentially methylated CpGs in specific regions of the genome. The protocol works with small amounts of DNA extracted from blood or semen. The protocol consists of both enzymatic conversion of unmethylated cytosines and capture by hybridization with a custom panel.
Nathalie Iannuccelli +4 more
wiley +1 more source
Fireballs (bolides) are high-energy luminous phenomena produced when meteoroids and small asteroids enter Earth’s atmosphere at hypersonic speeds, often resulting in fragmentation or complete disintegration accompanied by significant energy release.
Elizabeth A. Silber, Vedant Sawal
doaj +1 more source
Supernova Neutrino Light Curves from Cooling of High/Low-Mass Proto-Neutron Stars
Ken’ichiro Nakazato +1 more
openalex +2 more sources
Sphingoid base structures, the sphingolipid backbones, vary among species. We established yeast cells in which the native sphingoid base was replaced with plant‐type bases containing cis or trans double bonds. This is, to our knowledge, the first eukaryotic model mostly composed of sphingolipids containing cis‐unsaturated sphingoid base, providing a ...
Takashi Higuchi +5 more
wiley +1 more source
TESS Light Curve of the Interacting Binary W Serpentis
The unusal light curve of the massive eclipsing binary W Ser was recently observed with high S/N and fast cadence by the NASA TESS mission. The TESS light curve records two eclipses and relatively fast variations outside of the eclipses.
Douglas R. Gies +3 more
doaj +1 more source
CONSTRAINTS ON SHALLOW56Ni FROM THE EARLY LIGHT CURVES OF TYPE Ia SUPERNOVAE [PDF]
Anthony L. Piro, Ehud Nakar
openalex +1 more source

