Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
A time dependent relation between EUV solar flare light-curves from\n lines with differing formation temperatures [PDF]
E. Thiemann, F. G. Eparvier, T. N. Woods
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Molecular determinants of signal transduction in tropomyosin receptor kinases
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
The BSN Application-I: Photometric Light Curve Solutions of Contact Binary Systems [PDF]
Ehsan Paki +2 more
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Review of light curves of novae in the modified scales. II. Classical novae [PDF]
A. É. Rosenbush
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Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner +6 more
wiley +1 more source
Curved light sheet microscopy for centimeter-scale cleared tissues imaging [PDF]
Lijuan Tang +13 more
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Day-timescale variability in the radio light curve of the Tidal Disruption Event AT2022cmc: confirmation of a highly relativistic outflow [PDF]
Lauren Rhodes +11 more
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The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
SN 2009ip: CONSTRAINING THE LATEST EXPLOSION PROPERTIES BY ITS LATE-PHASE LIGHT CURVE [PDF]
Takashi J Moriya
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