Results 181 to 190 of about 2,321,585 (305)

Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam, Ali Laith, Aslihan Gunel, Melda Yilmaz, Nazli Basak, Halil Idrisoglu, P. Hande Ozdinler   +6 more
wiley   +1 more source

A Strong Jet Signature in the Late-time Light Curve of GW170817 [PDF]

, 2018
K. P. Mooley, D. A. Frail, Dougal Dobie, E. Lenc, A. Corsi, Kishalay De, A. J. Nayana, Sphesihle Makhathini, Ian Heywood, Tara Murphy, D. L. Kaplan, P. Chandra, O. Smirnov, Ehud Nakar, Gregg Hallinan, F. Camilo, R. P. Fender, S. Goedhart, P. Groot, M. M. Kasliwal, S. R. Kulkarni, P. A. Woudt   +21 more
openalex   +1 more source

Nationwide Characterization of MFN2‐Related CMT in 176 Japanese Patients: Clinical and Genetic Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Mitofusin 2 (MFN2) is a major causative gene for axonal Charcot – Marie – Tooth disease type 2A (CMT2A), with a wide phenotypic spectrum. Comprehensive large ‐ scale genotype – phenotype association studies are essential for understanding disease pathogenesis and improved clinical management.
Masahiro Ando, Yujiro Higuchi, Jun‐Hui Yuan, Akiko Yoshimura, Chikashi Yano, Takahiro Hobara, Fumikazu Kojima, Yu Hiramatsu, Satoshi Nozuma, Tomonori Nakamura, Yusuke Sakiyama, Jun Mitsui, Shoji Tsuji, Hiroshi Takashima   +13 more
wiley   +1 more source

Large-amplitude variability driven by giant dust storms on a planetary-mass companion. [PDF]

Sci Adv
Tan X, Zhang X, Marley MS, Zhou Y, Lew BWP, Miles BE, Batalha NE, Biller BA, Chauvin G, Hinkley S, Hoch KKW, Manjavacas E, Metchev S, Petrus S, Rickman E, Skemer A, Suárez G, Sutlieff BJ, Vos JM, Whiteford N.   +19 more
europepmc   +1 more source

The MMP‐9/TIMP‐1 Ratio and Concentrations of Osteopontin Are Elevated in Cerebrospinal Fluid of People With Multiple Sclerosis and Decrease After Autologous Hematopoietic Stem Cell Transplantation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic, Ida Erngren, Kim Kultima, Anders Larsson, Malin Müller, Anna Wiberg, Joachim Burman   +6 more
wiley   +1 more source

A key spectral tuning site of UV-sensitive vertebrate non-visual opsin Opn5. [PDF]

Cell Mol Life Sci
Yamashita T, Asamoto K, Fujii K, Fujiyabu C, Ohuchi H, Shichida Y.   +5 more
europepmc   +1 more source

BSN: Photometric Light Curve Analysis of Two Contact Binary Systems LS Del and V997 Cyg [PDF]

Atila Poro, Mehmet Tanrıver, Elham Sarvari, Shayan Zavvarei, Hossein Azarara, C. Laurent, Sabrina Baudart, Asma Ababafi, Nazanin Kahali Poor, Fariba Zare, A. Bulut, Ahmet Keskin   +11 more
openalex   +1 more source

DASCH 100-yr light curves of high mass X-ray binaries [PDF]

, 2013
M. Servillat, Sumin Tang, J. E. Grindlay, E. Los   +3 more
openalex   +1 more source

Prophylactic Management of Vestibular Migraine: A Systematic Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Vestibular migraine (VM) is a neurological disorder characterized by episodic vertigo in patients with migraine, contributing to substantial functional impairment. Although VM is relatively common, a consensus on effective prophylactic treatments is lacking.
Hussain Ali Almohammed, Husna Irfan Thalib, Kawthar Faisal Kushara, Bushra Wadi Bin Saddiq, Bayan Mohammed Khair Al Zoabi, Tanveer Nidal Khan, Ahmed Salah Morad, Rimas Warid Aljuaid, Lamyaa Mohammed Gharawi, Shahad Jawdat Alsaygh, Mable Pereira, Shaima Abuhulayqah   +11 more
wiley   +1 more source

Direct ambient photopatterning of RGB quantum dots for light-emitting diodes with EQE exceeding 20. [PDF]

Nat Commun
Guan J, Ma J, Zhou L, Zou Y, Ye L, Hou W, Zhang PK, Dai X, Zhang H, Talapin DV, Wang Y.   +10 more
europepmc   +1 more source