Results 91 to 100 of about 396,879 (255)

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Multilevel Fusion Network Based on Mix Hybrid Attention for Hyperspectral and LiDAR Image Classification

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
With the rapid development of remote sensing (RS) technology, the fusion of hyperspectral image (HSI) and light detection and ranging (LiDAR) data has shown great potential for improving land-cover classification accuracy. However, effectively leveraging
Ziping He, Qianglin Zhu, Wei Wang, Baokai Zu, Zhaohong Liu   +4 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Volumetric assessment of hepatic grafts using a light detection and ranging system for 3D scanning: Preliminary data. [PDF]

World J Hepatol, 2022
Katsanos G, Karakasi KE, Karolos IA, Kofinas A, Antoniadis N, Tsioukas V, Tsoulfas G.   +6 more
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Multimodal Prompt Tuning for Hyperspectral and LiDAR Classification

Remote Sensing
The joint classification of hyperspectral imaging (HSI) and Light Detection and Ranging (LiDAR) data holds significant importance for various practical uses, including urban mapping, mineral prospecting, and ecological observation.
Zhengyu Liu, Xia Yuan, Shuting Yang, Guanyiman Fu, Chunxia Zhao, Fengchao Xiong   +5 more
doaj   +1 more source

Smartphone-Based Light Detection and Ranging for Remote Patient Evaluation and Monitoring. [PDF]

Cureus, 2021
Bhandarkar AR, Bhandarkar S, Jarrah RM, Rosenman D, Bydon M.   +4 more
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Understanding the dynamic properties of trees using the motions constructed from multi-beam flash light detection and ranging measurements. [PDF]

J R Soc Interface, 2022
Chau WY, Loong CN, Wang YH, Chiu SW, Tan TJ, Wu J, Leung ML, Tan PS, Ooi GL.   +8 more
europepmc   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source