Results 111 to 120 of about 295,332 (287)

Enhanced light extraction efficiency and viewing angle characteristics of microcavity OLEDs by using a diffusion layer. [PDF]

Sci Rep, 2021
Park CH, Kang SW, Jung SG, Lee DJ, Park YW, Ju BK.   +5 more
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Enhanced light extraction by optimizing near-infrared perovskite-based light emitting diode (PeLED)

Scientific Reports
One of the outstanding optoelectronic devices is perovskite-based light emitting diodes (PeLEDs) that have diverse applications according to the wavelength of produced light.
Nava Tabibifar, Mehdi Eskandari, Farhad Akbari Boroumand, Davood Fathi, Saeed Rahimi   +4 more
doaj   +1 more source

Zirconia/phenylsiloxane nano-composite for LED encapsulation with high and stable light extraction efficiency. [PDF]

RSC Adv, 2021
Lu Y, Zhao Z, Fan X, Cao X, Hai M, Yang Z, Zheng K, Lu J, Zhang J, Ma Y, Zhang R, Fang S.   +11 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Enhancing Light Extraction Efficiency in Micro-LEDs via Metal Photonic Crystals in the Passivation Layer and Air Photonic Crystals on the n-GaN Side

IEEE Photonics Journal
Photonic crystals (PhCs), as a type of metamaterial, have attracted significant attention due to their ability to control light propagation to enhance the light extraction efficiency (LEE) of Micro-LEDs. However, the current advancements in improving the
Zhaoyong Liu, Gaoyu Dai, Kailin Ren, Luqiao Yin, Jianhua Zhang   +4 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Investigation on Wavelength-Dependent Light Extraction Efficiency of InGaN-Based Micro-LED Structures Using Numerical Simulations

Photonics
The external quantum efficiency (EQE) of InGaN-based LEDs typically decreases as wavelength shifts from blue to green to red. While this trend has often been attributed to the internal quantum efficiency of InGaN quantum wells (QWs), the influence of ...
Chibuzo Onwukaeme, Han-Youl Ryu
doaj   +1 more source

Investigation of Photonic-Crystal-Structured p-GaN Nanorods Fabricated by Polystyrene Nanosphere Lithography Method to Improve the Light Extraction Efficiency of InGaN/GaN Green Light-Emitting Diodes. [PDF]

Materials (Basel), 2021
Lei PH, Yang PC, Huang PC.
europepmc   +1 more source