Results 161 to 170 of about 295,332 (287)

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

Study of Sol gel-deposited ZnO Light Extraction Thin Films to Enhance the Efficiency in Organic Light-Emitting Diodes

open access: yes, 2017
In this study, we fabricated organic light-emitting diodes (OLEDs) with internal light extraction structure to reduce the Waveguide mode loss and increase the EQE by using the Sol\ue2gel-deposited ZnO light extraction thin films.
Su, Yen-cheng
core  

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer   +11 more
wiley   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng   +4 more
wiley   +1 more source

Study of Efficiency Enhancement in Organic Light-Emitting Diodes Utilizing Polyimide/SiO2 Composite Films as Light Extraction Layers

open access: yes, 2019
Organic light-emitting diodes (OLEDs) are being widely applied in displays owing to excellent characteristics. In the phosphorescence OLEDs, nearly 100% internal quantum efficiency can be achieved, but the external quantum efficiency is limited due to ...
Wang, Yi-Jyun
core  

Study on Packaging Technology of GAGG:Ce Scintillation Detector

open access: yesYuanzineng kexue jishu
GAGG:Ce scintillation crystal has a wide application prospect in the field of energy spectrum detection, due to its high density, high light yield, radiation resistance and non-deliquination characteristics.
WAN Qianyin1, 2, WANG Qiang1, 2, XIE Yuqing1, 2, XIAO Xiong1, 2, ZHANG Zetao1, 2, DING Yuchong1, 2, REN Kejing1, 2, XU Yang1, 2
doaj   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani   +10 more
wiley   +1 more source

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi   +5 more
wiley   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

open access: yesArthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos   +2 more
wiley   +1 more source

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