Results 121 to 130 of about 8,746,494 (343)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Precision optical model of asymmetry emission band of red light emitting diodes and its application in improving the color rendering index of white LEDs

open access: yesResults in Optics
We have proposed and demonstrated a precision optical model for red light-emitting diodes and applied this model to improve the color rendering index of phosphor-converted white light-emitting diodes.
Thi-Hanh-Thu Vu, Quang-Khoi Nguyen
doaj   +1 more source

Effect of wavelength and beam width on penetration in light-tissue interaction using computational methods

open access: yesLasers in Medical Science, 2017
Penetration depth of ultraviolet, visible light and infrared radiation in biological tissue has not previously been adequately measured. Risk assessment of typical intense pulsed light and laser intensities, spectral characteristics and the subsequent ...
C. Ash, M. Dubec, K. Donne, Tim Bashford
semanticscholar   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Controlling light tunneling by adiabatic passage in two modulated nonlinear waveguides

open access: yesResults in Physics, 2019
We theoretically investigate light propagation in two coupled nonlinear waveguides with a certain static propagation constant detuning between two waveguides and with the linear refractive index modulated along the propagation direction.
Jin Cui   +4 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Matching optics for Gaussian beams [PDF]

open access: yes, 1991
A system of matching optics for Gaussian beams is described. The matching optics system is positioned between a light beam emitter (such as a laser) and the input optics of a second optics system whereby the output from the light beam emitter is ...
Gunter, William D.
core   +1 more source

Input-output Gaussian channels: theory and application

open access: yes, 2012
Setting off from the classic input-output formalism, we develop a theoretical framework to characterise the Gaussian quantum channels relating the initial correlations of an open bosonic system to those of properly identified output modes.
Plenio, Martin B.   +3 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Interpretation of Light-Quenching Factor Measurements

open access: yes, 2007
We observe that the pattern of the quenching factors for scintillation light from various ions, recently studied in $CaWO_4$ in connection with dark matter detectors, can be understood as a saturation phenomenon in which the light output is simply ...
Angloher   +13 more
core   +1 more source

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