An ANGPTL8‐AKT2‐mTOR Axis Drives Adipose Senescence and Aging‐Related Functional Decline
ANGPTL8 increases with age in humans and mice and serves as a key predictor of biological aging and mortality. Adipocyte‐derived ANGPTL8 promotes cellular senescence through AKT2–mTOR signaling, whereas genetic deletion of Angptl8 attenuates adipose tissue aging and extends lifespan.
Yi He +11 more
wiley +1 more source
Enhancing internet of things intrusion detection through high-performance boosting ensemble learning. [PDF]
Yakovyna V, Fadieiev A.
europepmc +1 more source
Machine Learning of Personal Repertoires From Public T Cell Receptors
ABSTRACT The T‐cell receptor (TCR) repertoire records an individual's immunological history, but most unique CDR3 sequences in any one person are private and uninformative about anyone else. A small subset, however, recurs predictably across unrelated donors.
Or Malca, Alona Zilberberg, Sol Efroni
wiley +1 more source
Multi-task gradient boosting with multi-modal molecular representations for simultaneous prediction of drug clearance and volume of distribution. [PDF]
Lee GS, Choi HG, Park DK, Kim HY.
europepmc +1 more source
Study of a Kawasaki disease diagnostic prediction model based on the LightGBM machine learning algorithm. [PDF]
Li H +10 more
europepmc +1 more source
Development of a machine learning-based classification model for diabetic foot in patients with type 2 diabetes: an exploratory analysis with SHAP interpretation. [PDF]
Pei Y +9 more
europepmc +1 more source
Enhancing clinically cardiovascular machine learning model for risk prediction via sample augmentation. [PDF]
Tang X, Tang M, Liu W, Cui S.
europepmc +1 more source
Development and early feasibility testing of machine-learning algorithms to non-invasively assess hemoglobin levels. [PDF]
Hefner S +11 more
europepmc +1 more source
Arthralgia and fever as dominant predictors of Chikungunya confirmation: an explainable artificial intelligence approach. [PDF]
Lu X, Yin D, Zhang H.
europepmc +1 more source

