Results 61 to 70 of about 9,388,892 (203)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

A novel method for standardised imaging of corneal subbasal nerves by in vivo confocal microscopy – a pilot validation study

Scientific Reports
In vivo confocal microscopy is a valuable tool for evaluating corneal subbasal nerve plexus (SBNP). However, lack of standardised, repeatable, and reliable methods is a challenge, particularly in clinical, multi-centre, and longitudinal settings.
Siv A. Sandvik, Eilin Lundanes, Stephan Allgeier, Emanuele Käser, Neil Lagali, Jorunn Lid, Tove Lise Morisbakk, Vibeke Sundling   +7 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Dimming strategies for open office lighting : User experience and acceptance [PDF]

, 2018
Sensor-triggered control strategies can limit the energy consumption of lighting by considering the presence of users in the office and dimming lighting down when it is not needed. In multi-user offices, the application of occupancy-based dimming at room
Creemers, P.,, Rosemann, A. L. P.,, Rosemann, A.L.P., P Creemers, ALP Rosemann, van Loenen, E. J., Chraibi, S.,, Rosemann, ALP Alexander, Rosenkötter, C., Aries, Myriam,, MBC Aries, van Loenen, E. J.,, Chraibi, S Senna, Aries, MBC Myriam, EJ van Loenen, van Loenen, E.J., Loenen, EJ Evert van, Rosenkötter, C.,, C Rosenkötter, Chraibi, S., Aries, Myriam, Creemers, P., Creemers, PTJ Patrick, S Chraibi, Rosenkötter, CS Charlotte, Aries, M.B.C., Rosemann, A. L. P.   +26 more
core   +2 more sources

Análise de diferentes sistemas de iluminação para aviários de produção de ovos férteis Analysis of different illumination systems for poultry houses of producing fertile eggs

Revista Brasileira de Engenharia Agrícola e Ambiental, 2005
Excluindo-se a ração, o insumo mais utilizado na cadeia produtiva da avicultura é a energia elétrica, principalmente na produção de pintinhos de um dia, ocorrendo consumo em todas as fases, desde a obtenção do ovo até a incubação.
Rodrigo A. Jordan, Maria H. F. Tavares
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Lighting for Interior Design.

, 2012
Without light, interior architecture cannot be fully designed and experienced. It is one of the key tools for an interior designer, but can be a dauntingly technical subject for students.
Innes, Malcolm
core  

A review on methodological transitions in school lighting research from 1980 to 2020

Indoor Environments
This literature review aims to identify and discuss research studies exploring lighting in school environments from 1980 to 2020. The article explores how methods and tools, attributed to various research fields, have been used in education-related ...
Stavroula Angelaki
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source