Results 91 to 100 of about 359,657 (304)

Desain Lingkungan Kerja Berdasarkan Pendekatan Kesehatan dan Keselamatan Kerja

open access: yesOPSI, 2019
Kalasan Fried Chicken Industry Center is one of the home industries producing fried chicken in Yogyakarta. Initial measurements obtained from the working environment conditions of occupational health and safety are still considered to be less than ...
Eko Nursubiyantoro   +1 more
doaj   +1 more source

How Green Public Procurement Contributes to Sustainable Development in China: Evidence from the IISD Green Public Procurement Model [PDF]

open access: yes, 2015
The People's Republic of China spent more than CNY 1.6 trillion (USD 252 billion) on procurement in 2013, accounting for 11.7 per cent of all national spending (Ministry of Finance of the People's Republic of China, 2014).
Benjamin Denjean   +5 more
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Beyond Power over Ethernet : the development of Digital Energy Networks for buildings [PDF]

open access: yes, 2012
Alternating current power distribution using analogue control and safety devices has been the dominant process of power distribution within our buildings since the electricity industry began in the late 19th century.
Banks, Gerry   +3 more
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Effect of the green-emitting CaF2:Ce3+,Tb3+ phosphor particles’ size on color rendering index and color quality scale of the in-cup packaging multichip white LEDs [PDF]

open access: yes, 2018
In this paper, we investigate the effect of the green-emitting CaF2:Ce (3+), Tb (3+) phosphor particle's size on the color rendering index (CRI) and the color quality scale (CQS) of the in-cup packaging multichip white LEDs (MCW-LEDs).
Huynh, V. V.   +4 more
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Analisis Pencahayaan Ruang Kerja: Studi Kasus Pada Usaha Kecil Mikro dan Menengah (UMKM) Batik Tulis di Yogyakarta

open access: yesDinamika Rekayasa, 2013
A good workspace significantly affects on work productivity. Therefore, in designing a workspace, it is necessary to put much concern on lighting condition.
Dwi Handayani   +4 more
doaj  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

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