Results 121 to 130 of about 359,657 (304)

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Are cities under bright lights more innovative? Evidence from China

Heliyon
The prosperity of the nighttime economy is an important criterion for measuring urban development. Based on regression analysis of data from 330 prefecture-level cities in China, this study explores the potential link between urban lighting and urban ...
Zhenyu Jiang, Zhubo Li, Jianhua Wang
doaj   +1 more source

Application of BIM in sustainability analysis [PDF]

, 2010
Building Information Modeling (BIM) is the process of generating and managing building data during its life cycle. Typically it uses three-dimensional, real-time, dynamic building modeling software to increase productivity in building design and ...
Golzarpoor, Hamed
core  

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Investigating the Lighting Condition and Factors Affecting it in Industrial Workshops with Less than 20 Individuals in the Northeast Region of Isfahan City in 2023 [PDF]

Muhandisī-i bihdāsht-i ḥirfah/ī
Background and Objective: Appropriate lighting is one of the most valuable factors in optimizing physical conditions in workplaces, especially in industry, and it can increase efficiency and product quality.
Fereshteh Sadavipour, Habibullah Dehghan
doaj  

Research on the Impact of Lighting Illuminance and Color on Creative Performance and Mood

Buildings
With the development of the knowledge economy, the significance of the creative industry has become increasingly prominent. Individual creativity can be stimulated by optimal lighting.
Bo Zhou, Yangxiaoxiao Zhou, Qixuan Ren, Li Peng, Yang Guan, Haiyin He   +5 more
doaj   +1 more source

Delivering sustainable buildings in retail construction [PDF]

, 2012
Session: Sustainability: Theory and Design The article can be viewed at: http://www.arcom.ac.uk/-docs/proceedings/ar2012-1455-1465_Dangana_Pan_Goodhew.pdfThe demand for high performance 'green' or 'sustainable' buildings is becoming increasingly ...
Goodhew, S, Pan, W, Zainab, S
core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source