Results 111 to 120 of about 6,945,171 (251)

Lighting measurement in Shemiranat health center based on EN 12464-1 European standard

بهداشت و ایمنی کار, 2013
Introduction: Illumination standards especially Illumination Engineering Society of North America (IESNA) and Iran lighting standards (ILS) are just based quantitative measurements.
S H Koohpaye, S A Zakerian, H Kakooei
doaj  

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Improved indoor lighting improved healthy aging at home – an intervention study in 77-year-old Norwegians

Journal of Multidisciplinary Healthcare, 2019
Helle K Falkenberg,1 Tor Martin Kvikstad,2 Grethe Eilertsen31National Centre for Optics, Vision and Eye Care, Department of Optometry, Radiography and Lighting Design, University of South-Eastern Norway, Kongsberg, Norway; 2Department of Business ...
Falkenberg HK, Kvikstad TM, Eilertsen G
doaj  

Effects of different lighting programs on semi-heavy laying hens reared in open shelters [PDF]

Biotemas, 2010
The effects of of lighting programs on the zootechnic performance and egg quality of semi-heavy laying hens were evaluated. Three light programs were tested: continuous lighting of 15h (artificial+natural), intermittent lighting (two photophases of 15s ...
Henrique Jorge de Freitas, Judas Tadeu de Barros Cotta, Antonio Ilson de Oliveira, Luis David Solis Murgas, Clóvis Eliseu Gewehr   +4 more
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Investigating the effects of indoor lighting on measures of brain health in older adults: protocol for a cross-over randomized controlled trial

BMC Geriatrics
Background The worldwide number of adults aged 60 years and older is expected to double from 1 billion in 2019 to 2.1 billion by 2050. As the population lives longer, the rising incidence of chronic diseases, cognitive disorders, and behavioral health ...
Kevin A. Mazurek, Linhao Li, Robert J. Klein, Shengliang Rong, Aidan F. Mullan, David T. Jones, Erik K. St. Louis, Gregory A. Worrell, Christina Y. Chen   +8 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Light emitting diode (LED) lights for the improvement of plant performance and production: A comprehensive review

Current Research in Biotechnology
Light quality (spectral arrangement) and quantity (photoperiod and intensity) influence plant growth and metabolism and also interact with several factors including environmental parameters in defining the plant behavior.
Saikat Sena, Soni Kumari, Vijay Kumar, Azamal Husen   +3 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

On the photosynthetic responses of crops to intracanopy lighting with light emitting diodes [PDF]

, 2011
Key words: Cucumis sativus, intracanopy lighting, light-emitting diodes (LEDs), light distribution, light interception, light quality, photosynthesis, photosynthetic acclimation Assimilation lighting is a production factor of increasing importance in ...
Trouwborst, G.
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