Results 61 to 70 of about 3,062,912 (253)

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

The impact of artificial lighting on improving the visual experience of museum visitors: A case study of Sharjah Museum of Islamic Civilization

open access: yesHeritage and Sustainable Development
Lighting is a crucial element in museum design, directly influencing visitors’ psychological responses, visual experience, and overall satisfaction. Despite its significance, limited research exists on artificial lighting in museums within the United ...
Meera Alketbi, Emad Mushtah
doaj   +1 more source

Measuring the Lighting Quality in Academic Institutions: The UPM Faculty of Aerospace Engineering (Spain)

open access: yesApplied Sciences, 2020
This article analyzes the current status of the lighting quality at the Escuela Técnica Superior de Ingeniería Aeronáutica y del Espacio (ETSIAE), the aerospace engineering faculty at the Universidad Politécnica de Madrid (UPM), and evaluates possible ...
María Zamarreño-Suárez   +3 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Solar PV Lighting and Studying after Sunset: Analysis of Micro-benefits in Off-grid Rural Ghana [PDF]

open access: yes, 2013
Solar PV light provides school children living in off-grid rural communities the opportunity to have clean and bright lighting to study after sunset. On the contrary, lighting provided from poor sources can pollute and adversely affect human eyes during ...
George Y. , Obeng
core   +2 more sources

Computer Simulation of a Digital System of Automatic Lighting Control

open access: yesИнженерные технологии и системы
Introduction. In the poultry industry, the use of local LED lighting systems with changeable light and correlated color temperature of the luminaire optical radiation during the photoperiod is promising.
Evgeniy A. Shabaev   +1 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Savings in Cooling Energy with a Thermal Management System for LED Lighting in Office Buildings

open access: yesEnergies, 2015
Light-emitting diode (LED) lighting should be considered for lighting efficiency enhancement, however, waste heat from light-emitting diode (LED) lighting increases the internal cooling load during the summer season.
Byung-Lip Ahn   +5 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

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