Results 91 to 100 of about 43,246 (307)

Lightness Dependencies and the Effect of Texture on Suprathreshold Lightness Tolerances [PDF]

open access: yes, 2000
A psychophysical experiment was performed to determine the effects of lightness dependency on suprathreshold lightness tolerances. Using a pass/fail method of constant stimuli, lightness tolerance thresholds were measured using achromatic stimuli ...
Montag, Ethan D., Berns, Roy S.
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

The lightness of architecture

open access: yes, 2017
碩士輕作為現代建築中的一種現象,有多種背後的原因。本研究通過回顧建築師Buckminster Fuller、Frei Otto以及SANAA的建築思想和建築作品的起源與輕的關係,分析建築師對於建築“輕”的解讀以及他們對於建築“輕”的操作手法。從中可以看到,雖然“輕”是他們共同的著力點,但其背後表達的建築現象卻是不同的。“輕”既可以來自於科學的推演也可以來自於結構的優化,還可以來自於人們的感知。這些不同是建築師在建築與能源與人之間關係的背景下,對於不同建築問題解決的結果,這些建築問題包括材料,結構 ...
茆慧;Mao, Hui
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Effect of ultrasonic and infrared treatments on microbial population, physicochemical properties, and total phenols of sprouted wheat powder [PDF]

open access: yesفناوری‌های جدید در صنعت غذا
Sprouting is a simple technique for improving the nutritional and quality characteristics of cereal grains. The purpose of this work was to examine ultrasonic pretreatment and drying methods (hot-air and infrared) on microbial population (total bacterial
samira Amin-Ekhlas   +2 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

The influence of ultraviolet radiation on the colour of thermo-mechanically modified beech and oak wood

open access: yesMaderas: Ciencia y Tecnología, 2020
The study examined the influence of ultraviolet radiation on the colour of thermo-mechanically modified beech (Fagus sylvatica ) and oak (Quercus robur).
Agnieszka Laskowska
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

On Lightness

open access: yes, 1973
The intensity at a point in an image is the product of the reflectance at the corresponding object point and the intensity of illumination at that point. We are able to perceive lightness, a quantity closely correlated with reflectance.
Horn, Berthold K.P.
core  

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