Results 241 to 250 of about 407,660 (382)

Lightning and Atmospherics [PDF]

, 1936

openalex   +1 more source

Clinically relevant niclosamide concentrations modulate TMEM16A and CaV1.2 channels to control artery tone and capillary diameter

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose TMEM16A Ca2+‐gated Cl− channels mediate depolarisation of contractile vascular cells. The anthelmintic niclosamide was reported to modulate the TMEM16A channel, suggesting possible repurposing for vascular pharmacology. Here, we investigate the mechanism of TMEM16A modulation by niclosamide and explore its effect on the ...
Rachel Kaye, Claire Pearson, Tibyan Babiker, Emilio Agostinelli, Rumaitha Al‐Hosni, Paolo Tammaro   +5 more
wiley   +1 more source

Protection against Lightning [PDF]

, 1933

openalex   +1 more source

Effects of the P2RX4 antagonist BR11595 in a guinea pig model of chronic asthma

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Asthma is characterized by airway hyperresponsiveness (AHR), allergic inflammation, and airway remodelling. Although recent studies have shown that asthma pathophysiology involves P2X4 receptor activation, a potential link with chronic asthma remains to be explored.
Dan Li, Hoeke A. Baarsma, Melissa Mol‐van der Veen, Vicky Verschut, Kimberley S. Belfor, Tanja de Boer, Harm Maarsingh, Oliver Martin Fischer, Carolin Ebert, Hana Cernecka, Muriel Lizé, Reinoud Gosens, Loes Kistemaker, Martina Schmidt   +13 more
wiley   +1 more source

Mechanical Lichtenberg. [PDF]

Can Med Educ J
O'Reilly E.
europepmc   +1 more source

Aurora‐A Promotes Cell‐Cycle Progression From Quiescence Through Primary Cilia Disassembly

Cancer Science, EarlyView.
Our findings demonstrate that AurA facilitates cell cycle reentry by promoting primary cilia disassembly. Utilizing an inducible degron system, we showed that AurA depletion delays the G0/G1 transition, a defect rescued by forced deciliation. These results underscore AurA's role beyond mitosis and reinforce its potential as a therapeutic target in ...
Atsushi Kohso, Hironori Inaba, Masato T. Kanemaki, Esteban C. Gabazza, Hidemi Toyoda, Masahiro Hirayama, Hidemasa Goto   +6 more
wiley   +1 more source

Lightning-induced cataract with concomitant optic nerve damage. [PDF]

BMC Ophthalmol
Deng S, Gong D, Guo J, Dang K, Wang J.
europepmc   +1 more source

Designing, Developing and Examining the Effectiveness of a Machine Learning–Based Mobile Recommendation System for Parents' Digital Parenting Skills

Child &Family Social Work, EarlyView.
ABSTRACT It is of paramount importance that children are equipped with the requisite digital parenting skills to protect them from the risks and threats that they may encounter in the digital environment while also enabling them to seize the opportunities that the digital realm presents.
Yıldız Özaydin Aydoğdu, Hatice Yildiz Durak, Şeyhmus Aydoğdu, Sibel Somyürek, Tolga Güyer, Furkan Kurnaz   +5 more
wiley   +1 more source

Computer-assisted vacuum aspiration mechanical thrombectomy with Lightning Flash allows broader clinical application, enhanced procedural safety, and improved clinical outcomes for the treatment of acute and subacute iliofemoral and central deep venous thrombosis. [PDF]

J Vasc Surg Cases Innov Tech
Saleem T, Raju S.
europepmc   +1 more source

Phylogeography of the Anaspides richardsoni species clade (Anaspidacea, Anaspidesidae): glaciation and recolonization of the Tasmanian Central Plateau and the question of paraphyletic species

Cladistics, EarlyView.
Abstract We herein present a phylogenetic and population genetic analysis of a Tasmanian Mountain Shrimp clade, based on ddRAD and cytochrome oxidase subunit‐1 data sets. Our data show that the morphologically well‐delineated and widespread Anaspides richardsoni Ahyong, 2016 is paraphyletic with respect to four other species (A. eberhardi Ahyong, 2016,
Christoph G. Höpel, Shane T. Ahyong, Martin Kapun, Martin Schwentner, Stefan Richter   +4 more
wiley   +1 more source