Results 311 to 320 of about 391,025 (405)

Genetic and Pharmacological Inhibition of Metabotropic Glutamate Receptor Signalling Extends Lifespan in Drosophila

open access: yesAging Cell, EarlyView.
We show that genetic and pharmacological inhibition of the metabotropic glutamate receptor, DmGluRA extends Drosophila lifespan, improves stress tolerance and alters early‐life locomotion. Several markers indicative of reduced ribosomal biogenesis, a hallmark of longevity, were also detected in these flies.
Cui Guan   +4 more
wiley   +1 more source

Storylines: A science‐based method for assessing and measuring future physical climate‐related financial risk

open access: yesAccounting &Finance, EarlyView.
Abstract Regulators increasingly require organisations to disclose their climate‐related financial risks. Most future physical climate risks present unique challenges, however, as their likely occurrence and consequence cannot be quantified with veracity at business‐relevant scales.
Tanya Fiedler   +3 more
wiley   +1 more source

The Lived Experience of People With Intellectual Disability in Community Settings: A Comparison of Self‐Reports and Staff Reports

open access: yesBritish Journal of Learning Disabilities, EarlyView.
ABSTRACT Background There is a need for more qualitative research focusing on the lived experiences of people with an intellectual disability and a better understanding of how these experiences align with other voices in their lives, such as family and support staff. Methods In this qualitative study, we asked people with an intellectual disability (N =
Elizabeth Smith   +2 more
wiley   +1 more source

LIGHTNING EXPLODES DYNAMITE

open access: hybrid, 1924

openalex   +1 more source

Designing, Developing and Examining the Effectiveness of a Machine Learning–Based Mobile Recommendation System for Parents' Digital Parenting Skills

open access: yesChild &Family Social Work, EarlyView.
ABSTRACT It is of paramount importance that children are equipped with the requisite digital parenting skills to protect them from the risks and threats that they may encounter in the digital environment while also enabling them to seize the opportunities that the digital realm presents.
Yıldız Özaydin Aydoğdu   +5 more
wiley   +1 more source

Bracket Diffusion: HDR Image Generation by Consistent LDR Denoising

open access: yesComputer Graphics Forum, EarlyView.
Abstract We demonstrate generating HDR images using the concerted action of multiple black‐box, pre‐trained LDR image diffusion models. Common diffusion models are not HDR as, first, there is no sufficiently large HDR image dataset available to re‐train them, and, second, even if it was, re‐training such models is impossible for most compute budgets ...
M. Bemana   +4 more
wiley   +1 more source

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