Results 171 to 180 of about 63,606 (258)

Co‐localization of tau and TDP‐43 after extracellular vesicle delivery to cells

open access: yesThe FEBS Journal, Volume 293, Issue 5, Page 1495-1515, March 2026.
Extracellular vesicles (EVs) derived from donor cells transfected with EGFP–2N4R‐tau or mCherry‐wtTDP‐43 were taken up by recipient cells, leading to cytosolic co‐localization of tau and TDP‐43. Molecular modeling revealed that tau and TDP‐43 directly interact through hydrogen bonding, suggesting a mechanistic link underlying their co‐pathology ...
Farhang Aliakbari   +6 more
wiley   +1 more source

Comparative Study of Refractance Window and Hot Air Drying of Apple Pomace: Kinetics, Modeling, and Utilization in Pancakes

open access: yesJournal of Food Process Engineering, Volume 49, Issue 3, March 2026.
Refractance window drying efficiently valorized apple pomace by significantly reducing drying time and energy consumption while better preserving bioactive compounds compared to hot air drying. The resulting powder showed high functional potential and was successfully used as a sugar and flour substitute in pancakes.
Fadime Begüm Tepe, Tolga Kağan Tepe
wiley   +1 more source

The Stuck Electorate: Polarization, Nationalization, and the Consolidation of Party in the Trump Era

open access: yesPresidential Studies Quarterly, Volume 56, Issue 1, March 2026.
ABSTRACT The 2024 presidential election unfolded under extraordinary circumstances—the mid‐campaign withdrawal of an incumbent president, the nomination of the first woman of color by a major party, and the reelection of a president defeated 4 years earlier. Yet the outcome revealed an electorate that looked much like 2016 and 2020.
Jamie L. Carson, Stewart Ulrich
wiley   +1 more source

Clathrins Are Involved in the Endocytosis of Host Cytosol in the Malaria Parasite

open access: yesTraffic, Volume 27, Issue 1, March 2026.
This study characterized clathrin function in hemoglobin uptake from host red blood cells via the malaria parasite's specific endocytosis machinery, cytostome. Clathrin heavy chain, clathrin light chain, and AP‐1 γ subunit were found associated with certain proteins known to be involved in cytostome function, and they were localized at the collars of ...
Jun Miao   +10 more
wiley   +1 more source

Computed Tomographic Grading of Ear Diseases in Guinea Pigs (Cavia porcellus)

open access: yesVeterinary Radiology &Ultrasound, Volume 67, Issue 2, March 2026.
ABSTRACT Ear disease affecting the external and middle ears is a significant health concern in guinea pigs, which can be clinically silent and, if left untreated, can lead to severe and irreversible complications. Computed tomography (CT) is the primary imaging modality used to diagnose otitis in other species, particularly otitis media (OM).
Tara Brennan   +8 more
wiley   +1 more source

Systolic‐dominant coronary flow in rats and mice: Challenging the diastolic paradigm across conscious and anaesthetized states

open access: yesExperimental Physiology, Volume 111, Issue 3, Page 684-699, 1 March 2026.
Abstract Extensive research in humans, dogs, rabbits, rats, mice and other mammals has consistently demonstrated that coronary blood flow (CBF) peaks during ventricular diastole. For example, studies using transthoracic Doppler echocardiography in anaesthetized rats and mice, isolated blood‐perfused rat hearts and Doppler probes sutured to the ...
Heidi L. Lujan   +2 more
wiley   +1 more source

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