Results 41 to 50 of about 59,652 (188)

LD‐Net: A novel one‐stage knowledge distillation algorithm for lightning detection network

Meteorological Applications
Lightning often causes death, injury, and damage to various facilities and equipment. Accurately detecting the spatial location of lightning occurrence by predicting thunderstorms and lightning is of great significance.
Junjie Fu, Yingxiang Li, Jiawei Liu, Yulin Ji, Jiandan Zhong   +4 more
doaj   +1 more source

Inter-Comparison of Lightning Trends from Ground-Based Networks During Severe Weather: Applications Toward GLM [PDF]

, 2011
The planned GOES-R Geostationary Lightning Mapper (GLM) will provide total lightning data on the location and intensity of thunderstorms over a hemispheric spatial domain.
Bateman, Monte, Blakeslee, Richard J., Carey, Lawrence D., Cecil, Daniel J., Goodman, Steven J., Petersen, Walter A., Rudlosky, Scott D., Schultz, Chris J.   +7 more
core   +1 more source

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

Advanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang, Yaning Li, Jianxun Cai, Lisi Luo, Pengfei Yang, Yutong Chen, Jiancong Zhou, Yan Zeng, Jiaping Yu, Weiyu Zhang, Wenzheng Pang, Yufang Li, Chunhua Wen, Jian Li, Linjuan Zeng   +14 more
wiley   +1 more source

New Method for Single-Site Cloud-to-Ground Lightning Location Based on Tri-Pre Processing

Remote Sensing
The single-site lightning detection system can provide timely and effective information on lightning activity in areas where a multi-site lightning network cannot be built.
Bingzhe Dai, Qilin Zhang, Jie Li, Yi Liu, Minhong Zhao   +4 more
doaj   +1 more source

Lightning Geolocation and Flash Rates From LF Radio Observations During the RELAMPAGO Field Campaign

Earth and Space Science, 2021
The lightning data products generated by the low‐frequency (LF) radio lightning locating system (LLS) deployed during the Remote sensing of Electrification, Lightning, and Mesoscale/Microscale Processes with Adaptive Ground Observation (RELAMPAGO) field ...
A. Antunes de Sá, R. Marshall, W. Deierling   +2 more
doaj   +1 more source

Revisiting Lightning Activity and Parameterization Using Geostationary Satellite Observations

Remote Sensing, 2021
The Geostationary Lightning Mapper (GLM) on the Geostationary Operational Environmental Satellite 16 (GOES-16) detects total lightning continuously, with a high spatial resolution and detection efficiency.
Xin Zhang, Yan Yin, Julia Kukulies, Yang Li, Xiang Kuang, Chuan He, Jeff L. Lapierre, Dongxin Jiang, Jinghua Chen   +8 more
doaj   +1 more source

MGM as a Large‐Scale Pretrained Foundation Model for Microbiome Analyses in Diverse Contexts

Advanced Science, EarlyView.
We present the Microbial General Model (MGM), a transformer‐based foundation model pretrained on over 260,000 microbiome samples. MGM learns contextualized microbial representations via self‐supervised language modeling, enabling robust transfer learning, cross‐regional generalization, keystone taxa discovery, and prompt‐guided generation of realistic,
Haohong Zhang, Yuli Zhang, Zixin Kang, Jiayun Xiong, Ronghua Yang, Kang Ning   +5 more
wiley   +1 more source

Nanoparticle Immunoadjuvant Complexes Augment Germinal Center Responses to Vaccination

Advanced Science, EarlyView.
Scaffolding IL‐21 on the surface of a self‐assembling nanoparticle immunogen drives improved germinal center and humoral immune responses. These nanoparticle immunoadjuvant complexes (NICs) functionally modulate the germinal center driving improved somatic hypermutation and antibody maturation, suggesting this platform has potential utility as a ...
Nicholas J. Tursi, Colby J. Agostino, Jinwei Huang, Toshitha Kannan, Niklas Laenger, Jennifer Londregan, Katlyn Lederer, Michaela Helble, Nicole Bedanova, Cory Livingston, Ebony N. Gary, Madison McCanna, Marta Tarquis Medina, Rumi Habib, Ignacio Rodriguez Relaño, Ivan Maillard, Ami Patel, David Allman, Andrew Kossenkov, Amelia Escolano, Daniel W. Kulp, David. B. Weiner   +21 more
wiley   +1 more source

Three-Dimensional Lightning Characteristics Analysis over the Tibetan Plateau Based on Satellite-Based and Ground-Based Multi-Source Data

Atmosphere
Based on the data from the Chinese national ground-based (LFEDA: Low-frequency E-field Detection Array) and satellite-based lightning-detection systems (LMI: Lightning Mapping Imager), the spatial and temporal distribution statistical properties of all ...
Jie Zhu, Shulin Zhi, Dong Zheng, Zhengguo Yuan   +3 more
doaj   +1 more source

Selective Targeting of Immune Checkpoints HLA‐G and CD47 Using Novel Dual Signaling Protein DSP216 Promotes Innate Anticancer Immunity

Advanced Science, EarlyView.
The inhibitory immune checkpoints HLA‐G and CD47 are expressed on certain tumor types and inhibit immune cells in the tumor microenvironment. DSP216 binds specifically to cancer cells expressing both HLA‐G and CD47, and blocks their inhibitory signaling.
Lisa J. Jacob, Liat Tamir, Mufeed Abdeen, Ami Tamir, Alexandra Aronin, Itai Bloch, Roy Kahn, Iris Pecker, Mark Tykocinski, Gerwin Huls, Yaron Pereg, Ayelet Chajut, Edwin Bremer   +12 more
wiley   +1 more source