Cell Proliferation, EarlyView.The use of FG‐4592 in the process of myeloablation can promote haematopoietic cell apoptosis for more effective myeloablation, maintain the number of RBC and may create a pluripotent microenvironment suitable for donor cells, so as to enable more effective haematopoietic reconstruction of donor cells in vivo.
Guanheng Yang +8 more
wiley +1 more source
A lightning cluster identification method considering multi-scale spatiotemporal neighborhood relationships. [PDF]
PLoS OneShi M +6 more
europepmc +1 more source
Leadership and Accountability in Faith‐Based Institutions: Evidence From UK Mosques
Financial Accountability &Management, EarlyView.ABSTRACT This study investigates accountability in religious institutions on the basis of evidence obtained from interviews with relevant parties in UK mosques. We mobilize prior theoretical contention regarding servant leadership and constraints on personal accountability to expose perceptions of seriously deficient discharge outcomes.
Umair Riaz +3 more
wiley +1 more source
Assessment and Management of Electrical Injuries in Adults in the Emergency Department. [PDF]
CureusSmith I, Kidd S, Kim S, Tennill RM.
europepmc +1 more source
Human IDO2 exhibits unique binding affinities distinct to those of human IDO1
The FEBS Journal, EarlyView.Although indoleamine 2,3‐dioxygenase 2 (IDO2) is highly homologous to IDO1, it displays markedly lower catalytic activity. We found that IDO2 binds L‐tryptophan (L‐Trp) in a flipped orientation stabilized by the IDO2‐specific residue His143. Replacement of His143 with the IDO1‐equivalent tyrosine restored an IDO1‐like binding mode and increased ...
Shunsuke Nogi +8 more
wiley +1 more source
Protocol for metabolic profiling of antigen-specific CD8<sup>+</sup> T cells using spectral flow cytometry. [PDF]
STAR Protocde Graaf JF, Mülling N, Arens R.
europepmc +1 more source
The FEBS Journal, EarlyView.Fragile X messenger ribonucleoprotein 1 (FMRP) is a multidomain RNA‐binding protein associated with Fragile X Syndrome (FXS). We found that its N‐terminal structured region has an intrinsic propensity to undergo liquid–liquid phase separation and fibril formation. FXS‐associated mutations perturb protein stability and aggregation propensity, suggesting
Flavia Catalano +10 more
wiley +1 more source
Addressing lightning and market uncertainties in self-scheduling: A fuzzy-markov approach for smart grids. [PDF]
Sci RepBenistan IS, Shahbazzadeh MJ, Eslami M.
europepmc +1 more source
A Novel Approach for Thunderstorm and Lightning Detection System
International Journal of Science and Research (IJSR), 2017 openaire +1 more source
Unraveling the active site cover of coproheme decarboxylase from Listeria monocytogenes
The FEBS Journal, EarlyView.During heme biosynthesis in Gram‐positive bacteria, coproheme decarboxylase (ChdC) catalyzes the conversion of four‐propionate substrate coproheme to the two propionate product heme b. Its active site is universally covered by a flexible linking loop. This study identifies an important histidine residue, which stabilizes the loop in a ChdC homolog.
Nikolaus Falb +4 more
wiley +1 more source